Anaesthesia in Pulmonary disease Flashcards

1
Q

What factors reduce FRC in the intra-operative period

A
  1. Supine
  2. Anaesthetic agents
  3. Muscle relaxants
  4. Immobility
  5. Surgical retractors

–> Faster desaturation (depleted O2 reservoir) and increased work of breathing (compliance curve)

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2
Q

What are the overall effects of anaesthesia on respiratory function

A
  1. Reduced FRC
  2. Atelectasis
  3. Inhibited hypoxic/hypercapnoec/acidotic RSP response
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3
Q

What peak flow rate range suggests inadequate coughing and accumulation of secretions with increased risk of LRTI

A

< 200 L/min

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4
Q

How can it be determined that the bronchodilator status for a patient is optimal

A

FEV1 reversibility with BD is less than 15%.

IF reversibility is > 15 % or 200 mL then consider delaying the case to optimise bronchodilator therapy

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5
Q

What pre-operative interventions are effective with regard to the optimisation of respiratory function in order to improve post-operative outcomes

A
  1. Rx cardiac failure and LRTI
  2. STOP smoking
  3. Physiotherapy x 4 weeks (fitness/coughing/breathing technique)
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6
Q

Describe intra-operative risk reduction for improved outcomes in patients with respiratory disease

A
  1. Avoid fluid overload
  2. Lung Protective Ventilation
    - Vt: 6 - 8
    - Pmean < 30 cmH20
    - Ppeak < 35 cmH20
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7
Q

What post-operative interventions may improve postoperative outcomes

A
  1. Early mobilisation

2. Pain management

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8
Q

Define asthma

A

A chronic lung disease characterised by reversible episodic attacks of small airway obstruction due to bronchoconstriction, mucosal oedema and mucous plugging.

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9
Q

Describe the principles for intra-operative management of asthma

A

Avoid NSAID (cause bronchospasm)
Avoid drugs that release histamine (CIS/Morphine)
Avoid airway manipulation in light patient
Use drugs that cause BD: Volatiles/ketamine/MgSO4
Regional preferred

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10
Q

Describe IPPV for the asthmatic

A

Allow time for exhalation (I:E 1:4, Slow RR, higher Vt)

Permissive hypercapnoea ensure SaO2

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11
Q

Define apnoea

A

Cessation of airflow at the nose and mouth for at least 10 seconds.
- recurrent apnoea and hypoxaemia during sleep

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12
Q

What is STOP BANG

A

Snoring
Tiredness
Observed you stop breathing
Pressure (HPT)

BMI > 35
Age > 50
Neck circumference > 40
Gender: Male

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13
Q

What are the complications of OSA

A

Systemic HPT
Pulmonary HPT
CCF
RSP failure with CO2 retention

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14
Q

Which drugs pose a high risk for patients with OSA and why

A

Opioids (and sedatives)

  1. Distorted airway anatomy –> easy obstruction
  2. Increased sensitivity to opioids

Minimize opioids and observe in high care/ICU post op

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15
Q

How does smoking affect the risk of post-operative pulmonary complications

A

6 fold increase

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16
Q

What are the implications of smoking for anaesthesia

A
  1. 6 fold increase in POPC
  2. Associated with COAD, Ca lung, IHD, Vasc d/o
  3. Impaired mucociliary clearance
  4. Hyper-reactive airways
  5. Impaired immunity
  6. L shifted OHDC P50: reduced O2 delivery despite high SaO2 reading (COHb)
17
Q

How does preoperative cessation of smoking alter the risk in a smoking patient

A

Cessation for 8 weeks
- risks same as non smoker unless irreversible lung damage/disease

Cessation for 12 hours

  • COHb decrease –> improved DO2
  • Decreased nicotine stimulatory effects
18
Q

How long should patients who have had LRTI for elective surgery be postponed

A

6 weeks

Emergency surgery

  • Optimize with physio/nebulizer/antibioitcs
  • Attempt regional if feasible
19
Q

Discuss the preoperative assessment of a paediatric patient with URTI

A

Postpone for 2 weeks unless:

Experienced anaesthetist can proceed with caution
unless fever/purulent sputum (suggestive of acute viraemia or 2ndry bacterial infection)

20
Q

Describe the intra-operative complications of kids with URTI

A

Laryngospasm
Bronchospasm
Coughing
Desaturation