Anaemia Flashcards
1
Q
Normal blood Hb and haemltocrit level in males and females
A
- male Hb <130g/L Hct <0.38
- female Hb <120g/L Hct <0.37
2
Q
what is meant by plasma expansion
A
- plasma dilution
3
Q
What are reticulocytes
A
- red cells which just left BM
- larger than normal red cells
- polychromatic
4
Q
if MCV is low what does it mean?
A
- microcytic anaemia
- problems with haemoglobinisation
5
Q
high MCV meaning?
A
- macrocytic anaemia
-problems with maturation
6
Q
deficient haemoglobin synthesis (cytoplasmic defect)
A
Hypochromic microcytic anaemia
7
Q
In what cases % saturation of transferrin is decreased
A
- iron deficiency
- anaemia of chronic disease
8
Q
In what cases % of saturation of transferrin is increased
A
- genetic haemachromatosis
9
Q
Causes of hypochromic microcytic anaemia (TAILS)
A
- Thalassemia
- Anaemia of chronic disease
- Iron deficiency
- lead poisoning
- Sideroblastic anaemia
10
Q
which kind of iron supplement is used in paediatrics
A
- sodium feredetate (sytron)
- liquid prep with low iron conc
11
Q
in what situation should IV iron be given
A
- renal anaemia
- poor compliance/ tolerance to oral iron
12
Q
increased red cell production
A
regenerative anaemia
13
Q
what happens if there is reticulocytosis (destruction)
A
- increased unconjugated serum bilirubin
- increased urinary urobilinogen
- splenomegaly
14
Q
normochromic normocytic anaemia
A
- renal impairment
- marrow infiltration
- chronic disease
15
Q
how to differentiate between iron deficiency and anaemia of chronic disease
A
- ferritin is normal or increased in anaemia of chronic disease and decreased in iron deficiency
