Anaemia 1 Flashcards
1
Q
What are 4 causes of microcytic hypochromic anaemias?
A
IDA
Thalassaemia
Sideroblastic anaemia
ACD (usually normochromic)
2
Q
What does normal red cell production need?
A
EPO to drive erythropoiesis by making bone marrow make RBCs
Iron, B12 and folate
Minerals
Functioning bone marrow
No increased production or destruction of red cells.
3
Q
What is B12 needed for?
A
Methylation of homocysteine to methionine and methylmalonyl-coA isomerisation
