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Big Blue Topics > amphetamines > Flashcards

amphetamines Flashcards

1
Q

action

A

-promote release of catecholamines from neuronal binding sites into synaptic clef and then inhibiting their reuptake

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2
Q

acute ingestion

A

-increases MAC

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3
Q

chronic ingestion

A

-decreases MAC

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4
Q

metabolism

A

-oxidative deamination in liver

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5
Q

excretion

A
  • kdineys, enhanced by inc urine volume and acidification

- avoid alkaline urine b/c inc half life of amphetamines

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6
Q

sx of overdose

A
  • mydriasis, dry mouth, hyperhtermia, HTN, arrhythmia, restlessness, anxiety
  • severe HTN with reflex bradycardia
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7
Q

rx

A

midazolam and supportive measures

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Big Blue Topics (25 decks)

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