Amoeba(Intestinal) Flashcards
What is a protozoa
Single celled organism
Examples of intestinal amoebas
Entamoeba hysterical, polecki, coli gingiva, dispar
Endolimax nana
Entamoeba hysterical was discovered in
In dysenteric feces in 1875 by losch in Russia
Morphology of hystolytica
Trophozoite
Precyst
Cyst
What does hystolytica contain in precyst stage
Large glycogen granule and 2 chromatid bars
Immature and mature cyst of hystolytica
Immature : 1 nucleus and 1-4 chromatids
Mature: 2 successive divisions having 4 nuclei( quadrinucleated)
Excystation of mature cyst gives rise to
A metacyst .which divides to form metacystic trophozoites(amoebulae)
Incubation period of hystolytica
4days to 4 months
Diseases causes by hystolytica
Intestinal and extra intestinal amoebiasis
Lytic enzymes produced by trophozoites of hystolytica
Hystolysin.. damages mucosal epithelium
Cysteine proteinase and amoebic lectin cause inactivation of factor c3 and ionophore
Treatment of intestinal amoebiasis
Luminal amoebicides: iodoquinol, paromycin tetracycline
Tissue amoebicides: emetine, chloroquine
Tissue and luminal amoebicides: metronidazole, tinidazole, ornidazole
What are amphizoic organisms
Organisms that can multiply in host( endozoic) and free living conditions (exozoic)
A mature cyst of entamoeba coli contain
8 nuclei.. it’s non pathogenic commensal
Only intestinal amoebas without a cyst stage is?
Entamoeba gingivalis
Entamoeba hartmanni
Found wherever hystolytica is but does not ingest RBC.. similar to endolimax nana
