Amiodarone

Question 1

OLMC

Answer 1

None

Question 2

Supplied

Answer 2

150mg/3ml vials or pre-fills

Question 3

Indications

Answer 3

V-Fib/ Pulseless V-Tach, V-Tach with pulses

Question 4

Contraindications

Answer 4

none

Question 5

Precautions

Answer 5

1. In 3mg/ml or higher concentrations, may cause phlebitis. Infusion concentrations should not exceed 2mg/ml; 2. Will precipitate if used in same IV line as Sodium Bicarb or heparin

Question 6

Side effects and Notes

Answer 6

in perfusing pts, may cause low BP, prolonged QT, Torsades and V-Fib, severe braycardia and AV blocks; 2. non-cardiac toxicities are usually related to chronic administration and include pulmonary infiltrates, hepatic, and/or thyroid dysfunction and peripheral neuropathy

Question 7

Adult Dose

Answer 7

V-Fib/Pulseless V-Tach- 300 mg, repeat with 150 mg; V-Tach with a pulse- 150 mg mixed with 100 ml NS and infuse over 10 minutes

Question 8

Ped Dose

Answer 8

V-Fib/ Pulseless V-Tach- 5mg/kg may repeat x2 up to 15 mg/kg; V-Tach with a pulse- 5mg/kg over 20mg mixed with 2ml/kg NS, may repeat x2 up to 15mg/kg