Amino Acids Flashcards
Zwitterion
Nitrogen gains a proton, COOH loses proton. NH3+, COO-
Draw amino acid at room temperature/solid form
draw zwitterion
structure of zwitterion
giant ionic
reaction of two amino acids
firms dipeptide + water
disulfide bridges
between 2 cysteines after oxidation. Type of covalent bond therefore stronger than H bonds
peptide link
-CONH- amide bond
primary structure of protein
sequence
secondary structure of protein
shape, alpha helix or beta pleated sheet
tertiary structure of protein
the way the chain is folded, formed from H bonds and disulfide bridges
drugs for enzymes designed by
computer modelling
enzymes contain a
stereospecific active site
Cis-platin use
anti cancer drug
how does cis-platin work
bonds with guanine and stops DNA replication during cell division
How does cis-platin react
chloride ligands replaced by N on guanine, N uses LP to form coordinate bond
side effects of cis-platin
hair loss, fertility
complementary
A only hydrogen bonds to T, C only hydrogen bonds to G
monomers of DNA
nucleotides
Nucleotide contains
phosphate, sugar, base
sugar in DNA
2-deoxyribose
where does phosphate join in DNA
the OH at the top of the sugar
How do two nucleotides bond
OH at bottom of sugar bonds to phosphate of another nucleotide by taking off water
What part of the base bonds to sugar
NH
hydrogen bonds of base pairs
A T = 2 C G = 3
bond between 2 zwitterions
ionic NH3+ -OOC
