Amino acid ingestion and muscle protein synthesis Flashcards
muscle protein synthesis response to exercise and nutrition
exercise stimulates MPS
AAs stimulate MPS
exercise and AAs have synergistic effect on stimulation of MPS
synergistic
interaction to produce a greater effect
muscle protein breakdown response to exercise and nutrition
exercise improves net balance but without AAs positive values not reached
exercise and AAs increase MPB and results in positive protein balance
what is MPS max stimulated by?
20g of high quality protein
two groups of weightlifters - higher/low muscle mass
MPS measured following whole body resistance exercise and ingestion of:
- 20g whey
- 40g whey
total muscle mass doesn’t influence the response of MPS to protein following exercise
myofibrillar MPS
greater with 40g than 20g whey protein
amount of muscle mass activated during resistance exercise bout may be more important then total amount of muscle in body
dose-response r’ship
not that simple
what does split routine require after?
20-25g protein
what does whole body routine require after?
40g protein
older people and protein response
don’t respond as well to protein stimuli
lower MPS
whey protein and MPS
stimulates MPS to greatest extent following exercise training
whey and casein in milk
whey easier to digest
whey and lean body mass
whey stimulates greatest lean body mass gains following exercise training
casein digested slower - less increase in muscle
BCAA
alome stimulates MPS
less than whey
leucine
addition to suboptimal doses of protein increases MPS rates in young with resistance exercise
and to other macronutrients of protein increases MPS rates in young
- whey has high amounts of leucine - switched PS on in sufficient amounts
and to casein increases MPS rates in elderly