Amebae and Balantidium Flashcards
deaths from Amebiasis are highest in ____, people of ___ & ____ descent, and people who are age ____ or above
males, Hispanic, Asian/Pacific Islander, 75
deaths from Amebiasis are associated with ____ infection
HIV
more than 40% of fatal amebiasis occur in which states?
CA & TX
where is Entamoeba histolytica found?
distributed all over the world
what is the reservoir for Entamoeba histolytica?
humans
true or false: many protozoan species in the genus Entamoeba colonize humans, but NOT all are associated with disease
true
E. histolytica is pathogenic as it gobbles up ___, but E. _____ is noninvasive, but is morphologically _______ from E. histolytica
RBCs, dispar, indistinguishable
describe the lifecycle of E. histolytica
an individual who is infected will shed cysts and trophozoites. the trophozoites will not survive, but the cysts are hardy and can survive in the environment for days-weeks, until they’re ingested by a human. once inside a human, the cyst transforms into trophozoites.
name symptoms that fall under “invasive intestinal amebiasis”
- dysentery, ulceration/inflammation of colon
- appendicitis
- toxic megacolon
- amebomas (granuloma that forms around the amoeba)
name symptoms that fall under “invasive extraintestinal amebiasis”
- liver abscess
- pleuropulmonary abscess
- cutaneous and genital amebic lesions
- brain hemorrhages (bleeding)
the content from amebic abscess have a ______ color
chocolate
skin infections from E. histolytica can be intense in the _____ region, because the _____ are excreted and can divide in the surrounding tissue
perianal, trophozoites
how to diagnose amebiasis?
- first try to see the parasites
- rule out with 3x stool exam
- fresh stool wet mount & permanent stain
- biopsy
- liver scan, CT scan, ultrasound
a modern way to diagnose E. histolytica?
PCR (E. histolytica is on the multiplex PCR panel)
size of E. histo/dispar trophozoite?
15-20 microns (15-60 range)
appearance of E. histo/dispar trophozoite?
single nucleus w/ central karyosome, peripheral chromatin
erythrophagocytosis is a clue for E. ____
histolytica
what is the appearance of the cytoplasm of E. histo/dispar trophozoites?
ground glass cytoplasm
E. histo/dispar trophozoites are typically found in _____ stool, while the cyst forms are usually found in ______ stool
diarrheal, formed
how many nuclei are in the cysts of E. histo/dispar?
4 nuclei
what else does the cyst of E. histo/dispar contain?
chromatoidal body
for E. histo/dispar, 1 cyst gives rise to __ trophozoites
4
the chromatid body for E. histo/dispar has _____ ends
rounded