Alzheimers, Periph Neuropathy

Question 1

What structures is affected in mild cog impairment AD? symps?

Answer 1

-med temporal lobe
-symps: short term memory loss

Question 2

What structures is affected in mild AD? symps?

Answer 2

-lateral temporal and parietal lobes
-symps: reading probs, poor object recognition, poor direction sense

Question 3

What structures is affected in mod AD? symps?

Answer 3

-frontal lobe
-symps: poor judgement, impulsive, short attention

Question 4

What structures is affected in severe AD? symps?

Answer 4

-occipital lobe
-symps: visual probs

Question 5

What is irisin

Answer 5

Protein released w/ ex that “slows down” AD

-enhances memory and learning
-increases neuroplasticity
-suppresses plaques
-decreases neuroinflam

Question 6

What two things can ex help with

Answer 6

Neuro protection and cognitive improvement

Question 7

S/S of peripheral neuropathy

Answer 7

-impaired vib
-glove and stocking anesthesia
-ft drop
-loss of ankle DTR
-ulcers/slow healing
-shoot/burn pain

Question 8

Types of sensory abnormalities - peripheral neuropathy

Answer 8

-absent/diminished
-parenthesia (pins and needles)
-hyperesthesias
-causalgia (burning pain)
-allodynia

Question 9

Describe the 5 step sensory loss progression for peripheral neuropathy

Answer 9

Sensory loss and abnorm force generation
Abnormal jt forces
Skin degeneration
Breakdown and ulcer
Infection, gangrene, amputation*

Question 10

Describe the 5 step motor loss progression for peripheral neuropathy

Answer 10

Abnorm force generation and sensory loss
Abnorm jt forces
Mus weak
Ataxia
Decreased balance and falls

Question 11

Fall prevention starts for peripheral neuropathy

Answer 11

-edu and activities
-footwear: low heels and firm rubber soles to enhance proprioception

Question 12

Describe the best activity program for peripheral neuropathy

Answer 12

-low impact ex
-stx, esp ankles (increase ankle strat)

Question 13

5 main motor dysfxn with peripheral neuropathy

Answer 13

-weakness (loss DTR)
-decreased balance
-increased latencies
-increased response times
-ataxia

Question 14

What are 5 characteristics of typical presentation of diabetic neuropathy

Answer 14

-distal symps
-bilateral
-polyneuropathy
-stocking/glove
-LE initially

Question 15

How do skeletal dysfxns of peripheral neuropathy occur. Examples

Answer 15

-abnorm WB forces d/t sensory loss
-bunions, toe clawing, valg deforms, arch and toe deforms