Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharm Penultimate Exam > Alzheimer's Disease > Flashcards

Alzheimer's Disease Flashcards

1
Q

What are the three currently available cholinesterase inhibitor Alz drugs.

A

Galantamine
Donepezil
Rivastigmine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Why do cholinesterase inhibitors help AD?

A

They help compensate for the loss of acetylcholine that results from the degeneration of cholinergic nerve terminals in AD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Specific details on Galantamine

A

Selective, Reversible inhibitor of acetylcholinesterase

Enhancer of action of ACh on nicotinic receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Specific details on Donepezil

A

Specific, Reversible inhibitor of AChase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Specific details on Rivastigmine

A

Inhibitor of AChase AND butyrylcholinesterase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Alz treatment that utilizes anti-glutamatergic therapy

A

Memantine

(Mg also has an effect, btu Mem stays longer, has a better decrease in Ca influx.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Memantine specific details

A

NMDA antagonist that blocks glutamatergic neurotransimission via noncompetitive mechanism.
Excess glutamate leads to excitotoxicity, neuronal death

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

New beta amyloid imaging technique for AD

A

Florbetapir

How well did you know this?
1
Not at all
2
3
4
5
Perfectly

Pharm Penultimate Exam (12 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions