ALS & Guillain Barre Pharm (Exam 2)

Question 1

riluzole: class

Answer 1

Glutamate inhibitor

Question 2

riluzole: Indication

Answer 2

Only drug approved for ALS

Question 3

riluzole: MOA

Answer 3

Glutamate antagonist

Reduces damage to motor neurons

Question 4

Does riluzole increase life expectancy?

Answer 4

Yes, it has been shown to prolong survival

By like half a year or so

Question 5

riluzole: Adverse effects

Answer 5

Dizziness

GI upset

Hepatotoxicity

Question 6

GBS: Pharmacotherapy

Answer 6

-Steroid therapy (start high and taper down as they recover)

-High-dose immunoglobulin therapy (IV)

Question 7

GBS: High Dose Immunoglobulin Therapy

Answer 7

Shorten severity and duration