Alpha-and Beta-Adrenergic Agonists Flashcards
Epinephrine (Brand Name)
[Prototype]
Adrenalin, Sus-Phrine, Epi-Pen
Epinephrine (Indication)
[Prototype]
Treatment of shock when increased BP and heart contractility are essential; to prolong effects of regional anesthetic; primary treatment for bronchospasm; to produce a local vasoconstriction that prolongs the effects of local anesthetics
Epinephrine (Mechanism for Action)
[Prototype]
- affects both beta1(cardiac) and beta2(pulmonary)-adrenergic receptor sites
- bronchodilation
- alpha-adrenergic agonist properties, resulting in vasoconstriction
- inhibits release of mediators of immediate hypersensitivity reactions from mast cells
Epinephrine (Adverse Effects)
[Prototype]
CNS: nervousness, restlessness, tremor, H/A, insomnia
Resp: paradoxical bronchospasm
CV: angina, arrhythmias, HTN, tachycardia
GI: N&V
Endo: hyperglycemia
Epinephrine (Client Education)
[Prototype]
- Caution pt not to exceed recommended dose; may cause adverse effects, paradoxical bronchospasm or loss of effectiveness of medication.
- Inhalers: Advise pt to rinse mouth with water after each inhalation dose to minimize dry mouth. Maintain adequate fluid intake.
- Autoinjector: instruct pts using injector for anaphalaxis to remove gray cap, place black tip on thigh at rt angle to leg. Press hard into thigh, hold in place for 10 secs, massage injected area for 10 secs.
Epinephrine (Interactions)
[Prototype]
D-to-D: concurrent use with other adrenergic agents will have additive adrenergic side effects; use with MAO inhibitors may lead to hypertensive crisis; beta blockers may negate therapeutic effect; Tricyclic antidepressants enhance pressor response to epi.
D-to-NP: Use with caffeine-containing herbs will increase the stimulant effect
