Allergy and hypersensitivity

Question 1

4 classifications of hypersensitivity

Answer 1

1- atopic allergy (IgE mediated) immediate
2-complement mediated medium
3-serum sickness (immune complexes) medium
4-delayed type DTH slow responde

Question 2

Atopic allergy

Answer 2

IgE produces B cells early in life that are challenged by allergies and develops inappropriate IgE producing B cells

Question 3

Type 2

Answer 3

Normal phagocytosis
When phagocytes meet rbc that has RH antigen it adheres to surface of rbc and initiates complement cascade and digests walls of rbc killing it

Question 4

Rhesus baby

Answer 4

Mother develops antibodies to RhD antigen.
To cure is injected with anti Rh antibodies to destroy fetal rbc so mother cant stimulate immune response

Question 5

Treatment or allergy by desensitisation

Answer 5

Make high affini6 IgG to compete with IgE

Question 6

Monoclonal antibodies

Answer 6

Designed to target specific antigens. Produced by cloning B cell and replicating.