Allergies Flashcards
type I hypersensitivity
IGE mediated allergies
how allergies rxn occur?
exposure to trigger
mast cells cross link
mast cells degranulate
histamine release = rxn
anaphylaxis vs urticaria vs angioedema?
anaphylaxis: hives + hypotension(low BP) + wheezing
anaphylaxis dx
clinical
anaphylaxis tx
epinepherine 1:1000 IM
- H1 and H2 blockers
- steriods
urticaria rash
wheal
whelt
erythema
no hypotension = no anaphylaxis
t/f urticaria SL?
true
bite / sting? bee allergies? how tx
anaphylaxis: treat epi
not: remove pincer, topical
angioedema def
swelling, stridor,
recent ACEI use
*wont break out in hives, no hypotension
examples H1 and H2 blockers
H1: diphenhydramine (benadryl), fexofinadine (allegra), cetirizine (zyrtec)
H2: Ranitidine (zantac), Famotidine, Nizatadine, Cimetidine
chronic allergic rhinitis nasal polyps
pale boggy mucosa
when is allergic skin testing necessary
only when refractory to the therapy or want to do desensitization therapy
allergic rhinitis tx
H1, H2 blockers
intranasal steriods #1
pediatric allergy med?
zyrtec (cetirizine) have to be 2+
allegra (fexofinidine) suspension safe 6 months
typical allergens that cause anaphylaxis
nuts, shellfish