Allergic Rhinitis Cough

Question 1

Describe stimulation of sensory receptors that produce cough

Answer 1

The epithelium of the larynx, trachea, and larger bronchi (Tracheobronchial tree) contains sensory nerves that are responsible for cough
this is vagally mediated

Question 2

What location of the brain initiates involuntary cough

Answer 2

initiated by the “cough center” in the medulla oblongata of brainstem

Question 3

What location of the brain initiates cerebral cough

Answer 3

cerebral cortex

Question 4

what infectious agent may increase the receptor sensitivity

Answer 4

viruses

Question 5

common cause of an acute cough

Answer 5

commonly it is a viral URTI, should last less than 3 weeks

Question 6

common cause of subacute cough

Answer 6

commonly it is a bacterial infection or asthma, should last 3 to 8 weeks

Question 7

common cause of chronic cough

Answer 7

commonly caused by postnasal drip syndrome, GERD, or astham, lasting longer than 8 weeks

Question 8

Hydrocodone/Codeine mechanism of action

Answer 8

works as a cough suppressant, has direct central action in the medulla

Question 9

Hydrocodone/Codeine C-II and C-III

Answer 9

C-II acts as a solitary agent, C-III acts in combination

Question 10

Hydrocodone/Codeine formulations

Answer 10

Codeine/Guiafenesin (Robitussin AC)
Codeine/Promethazine (Phenergan with Codeine)
Hydrocodone/Chlorpheniramine (Tussionex)

Question 11

which of the Hydrocodone/Codeine formulations last the longest?

Answer 11

Hydrocodone/Chlorpheniramine (Tussionex)

Question 12

Hydrocodone/Codeine contrainfictions

Answer 12

hypersensitivity

Question 13

Hydrocodone/Codeine Adverse Reactions

Answer 13

CNS depressants
Drug abuse/ dependency
Nausea

Question 14

Hydrocodone/Codeine Drug Interactions

Answer 14

CNS depressants may enhance toxicity

Question 15

What should you monitor in patients taking Hydrocodone/Codeine

Answer 15

Underlying conditions

Frequency of use

Question 16

Benzonatate Mechanism of action

Answer 16

Suppresses the cough by a topical anesthetic action on the respirator stretch receptors

Question 17

which cough medication in a relative to tetracaine

Answer 17

benzonatate

Question 18

Benzonatate contraindicatins

Answer 18

Hypersensitivity to related compounds

Increased risk of death in children under 10 years old

Question 19

Benzonatate Adverse Reactions

Answer 19

Mental confusion
Visual hallucinations
Sedation

Question 20

What should you monitor in patients taking Benzonatate

Answer 20

their underlying conditions

Question 21

Benzonatate Drug Interactions

Answer 21

no significant interactions

Question 22

Dextromethorphan Mechanism of action

Answer 22

Decreases sensitivity of cough receptor by suppressing the medullary cough center

Question 23

which cough treatment is structurally related to codeine?

Answer 23

Dextromethorphan

Question 24

Dextromethorphan contraindications

Answer 24

MAOI administration within 2 weeks

Question 25

Dextromethorphan Adverse Reactions

Answer 25

confusion | potential serotonin syndrome

Question 26

Dextromethorphan Drug Interactions

Answer 26

when taken with SSRIs can enhance the serotonergic effect

Question 27

What should you monitor in patients taking Dextromethorphan?

Answer 27

underlying conditions as well as abuse to misuse

Question 28

Guaifenesin Mechanism of action

Answer 28

Irritating gastric mucosa and stimulating respiratory tract secretions results in increased respiratory fluid volumes and decreases mucous viscosity

Question 29

Describe Guaifenesin

Answer 29

also know as Mucinex, having both immediate and extended release formulations make sure patients take large glasses of water when taking this treatment to increase it's ability to treat cough

Question 30

Guaifenesin contraindications

Answer 30

hypersensitivity

Question 31

Guaifenesin adverse reactions

Answer 31

dizziness, drowsiness headache nausea, vomitting

Question 32

Guaifenesin drug interactions

Answer 32

no significant interactions

Question 33

What should you monitor in patients taking Guaifenesin?

Answer 33

underlying conditions and hydration status