Alfaxalone Flashcards

1
Q

What us alfaxalone classed as?

A

A neuro-active steroid anesthetic

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2
Q

What does alfaxalone do?

A
  • Produces good hypnosis and reasonable muscle relaxation
  • Decreases cerebral blood flow, intracranial pressure and cerebral metabolic oxygen requirements
  • Dose dependent hypotension initially due to myocardial depression and peripheral vasodilation - effects usually offset by reflex tachycardia
  • minimal respiratory depression
  • effects are non-cumulative
  • IV and CRI acceptable
  • IM possible but less effective unless its deep muscle
  • no histamine release or pain on injection
  • no preservative - once opened must discard in 7 days
  • excitment seen on recovery if it’s the only agent on board
  • no analgesia
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