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Y2 CLASP > Alcoholism > Flashcards

Alcoholism Flashcards

1
Q

what screening test is used for alcoholism

A

AUDIT

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2
Q

define harmful use

A

physical or mental damage due to alcohol persisting for at least 1 month

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3
Q

define alcohol dependence syndrome

A 
>3 of 
desire/compulsion for alcohol
difficulty controlling use
persistent use despite evidence of harm
substance use
>tolerance
psychological withdrawal state
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4
Q

management of alcohol withdrawal

A

vitamins + chlordiazapoxide or diazepam

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5
Q

what vitamins for high and low risk

A

low risk PO thiamine, high risk IM Pabrinex

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6
Q

when should pharmacological relapse prevention begin

A

after acute withdrawal

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7
Q

what is pharmacological relapse prevention

A

acamprostate or disulfiram

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8
Q

other name for disulfiram

A

antabuse

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9
Q

acamprostate mechanism

A

decreases alcohol craving

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10
Q

disulfiram mechanism

A

aversion therapy, inhibits aldehyde dehydrogenase

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11
Q

where is aspiration pneumonia most likely

A

right lower lobe

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12
Q

what is beriberi

A

B1 thiamine deficiency

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13
Q

long term effect of alcohol on the heart

A

dilated cardiomyopathy not hypertrophic

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14
Q

general presentation of thiamine deficiency

A

decreased sensation / weakness in limbs

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15
Q

which arrhythmia is alcoholism a risk factor for

A

long QT syndrome

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16
Q

what is alcoholic steatosis

A

triglyceride accumulation in hepatocyte

17
Q

appearance of alcoholic steatosis on histology

A

white fat within hepatocytes, Mallory bodies

18
Q

what vitamin deficiency causes night blindness

A

vit a

19
Q

when does delirium tremens occur

A

2-3 days after last drink

20
Q

presentation of delerium tremens

A

sudden hallucination / nervous system change

21
Q

management of delerium tremens

A

IV fluid, anticonvulsant, antiemetic, antipsychotic

22
Q

cause of portal hypertension

A

cirrhosis

23
Q

why does alcohol increase cancer risk

A

acetaldehyde carcinogenic

24
Q

which cancers is alcohol associated with

A

oral, pharyngeal, laryngeal, oesophageal, colorectal, hepatocellular carcinoma, breast, pancreatic

25
Q

what is boerrhave syndrome

A

gastric rupture

26
Q

risk factor for alcoholic ketoacidosis

A

malnutrition

27
Q

menthol poisoning treatment

A

ethanol

28
Q

what is holiday heart syndrome

A

AF or SVT on > ethanol consumption

29
Q

commonest cause of methanol poisoning

A

antifreeze ingestion

30
Q

pathology of methanol poisoning

A

acidic metabolites cause toxic acidosis

31
Q

classification of withdrawal

A

mild
moderate
severe

32
Q

what is seen on biochemistry in methanol poisoning

A

osmolal gap

Y2 CLASP (6 decks)

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