Alcoholism Flashcards

(32 cards)

1
Q

what screening test is used for alcoholism

A

AUDIT

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2
Q

define harmful use

A

physical or mental damage due to alcohol persisting for at least 1 month

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3
Q

define alcohol dependence syndrome

A
>3 of 
desire/compulsion for alcohol
difficulty controlling use
persistent use despite evidence of harm
substance use
>tolerance
psychological withdrawal state
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4
Q

management of alcohol withdrawal

A

vitamins + chlordiazapoxide or diazepam

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5
Q

what vitamins for high and low risk

A

low risk PO thiamine, high risk IM Pabrinex

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6
Q

when should pharmacological relapse prevention begin

A

after acute withdrawal

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7
Q

what is pharmacological relapse prevention

A

acamprostate or disulfiram

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8
Q

other name for disulfiram

A

antabuse

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9
Q

acamprostate mechanism

A

decreases alcohol craving

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10
Q

disulfiram mechanism

A

aversion therapy, inhibits aldehyde dehydrogenase

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11
Q

where is aspiration pneumonia most likely

A

right lower lobe

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12
Q

what is beriberi

A

B1 thiamine deficiency

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13
Q

long term effect of alcohol on the heart

A

dilated cardiomyopathy not hypertrophic

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14
Q

general presentation of thiamine deficiency

A

decreased sensation / weakness in limbs

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15
Q

which arrhythmia is alcoholism a risk factor for

A

long QT syndrome

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16
Q

what is alcoholic steatosis

A

triglyceride accumulation in hepatocyte

17
Q

appearance of alcoholic steatosis on histology

A

white fat within hepatocytes, Mallory bodies

18
Q

what vitamin deficiency causes night blindness

19
Q

when does delirium tremens occur

A

2-3 days after last drink

20
Q

presentation of delerium tremens

A

sudden hallucination / nervous system change

21
Q

management of delerium tremens

A

IV fluid, anticonvulsant, antiemetic, antipsychotic

22
Q

cause of portal hypertension

23
Q

why does alcohol increase cancer risk

A

acetaldehyde carcinogenic

24
Q

which cancers is alcohol associated with

A

oral, pharyngeal, laryngeal, oesophageal, colorectal, hepatocellular carcinoma, breast, pancreatic

25
what is boerrhave syndrome
gastric rupture
26
risk factor for alcoholic ketoacidosis
malnutrition
27
menthol poisoning treatment
ethanol
28
what is holiday heart syndrome
AF or SVT on > ethanol consumption
29
commonest cause of methanol poisoning
antifreeze ingestion
30
pathology of methanol poisoning
acidic metabolites cause toxic acidosis
31
classification of withdrawal
mild moderate severe
32
what is seen on biochemistry in methanol poisoning
osmolal gap