Alcohol Used Disorder

Question 1

Binge Drinking

Answer 1

-male-5+ drinks in 2 hour period
female-4+ drinks in a 2 hour period

Question 2

Heavy drinking

Answer 2

male: 15 or ore drinks per week
female: 8 or more drinks a week

Question 3

alcohol use disorder

Answer 3

-medical diagnosis made on criteria made based on the DSM-5
-either mild(2-3), moderate(4-5), severe(6+) depending on how many criteria are met

Question 4

Screening for AUD

Answer 4

-treatable condition
-only 10% of individuals recieve treatment

Question 5

in chronic alcohol use, what causes the severe effects of alcohol withdrawal?

Answer 5

-alcohol is a GABA agonist so our body over compensates by making more glutamate to be in equilibrium
0when stopping drinking, GABA drops, glutamate activity is still high

Question 6

CIWA

Answer 6

-used to know how bad alcohol withdrawal is
-assessment tool

Question 7

Post acute withdrawal syndrome

Answer 7

-second phase of withdrawal symptoms as brain recalibrates after addiction
-lasts up to 3 months

Question 8

Medically Managed Withdrawal

Answer 8

-use medications to manage alcohol withdrawal
-anyone experiancing withdrawal symptoms or at high risk for withdrawal symptoms is a candidate

Question 9

Benzodiazepines

Answer 9

-enhance GABA effects by binding to benzo receptors
-recommend treatment for mild to severe alcohol withdrawal
-CIWA>10

Question 10

Gabapentin

Answer 10

-GABA analog
-safe and effective alternative to benzodiazepine for treatment for mild alcohol withdrawal in out patient
-CIWA <10

Question 11

Naltrexone

Answer 11

-mu opioid receptor antagonist
reduces perceived enjoyment of drinking alcohol and may decrease cravings

Question 12

Acamprosate

Answer 12

-reduces alcohol cravings
-6 tablets per day!!!
-Contraindicated CrCl <30

Question 13

Disulfiram

Answer 13

-blocks acetaldehyde dehydrogenase
-makes people sick when they drink
-does not decrease cravings
-avoid alcohol for 14 days