Alcohol Flashcards
What does a pharmacologist do?
Looks at effects of drugs
What is alcohol?
Ethanol- CH3CH2OH
Colourless
Found in alcoholic drinks and other products (e.g. Mouthwash and perfume)
What is the English drink drive limit?
80mg/100ml blood
What does 20mg/100ml blood do?
Low level, one unit
Disinhibition
-depresses inhibition, euphoria, release of social and sexual inhibitions
What does 80mg/100ml of blood do?
Disinhibition of emotions and social and sexual inhibitions become more pronounced
Motor co-ordination becomes affected
Marked effect on judgement
What does 200mg/100ml of blood do?
10 units
Motor coordination is progressively worse
Speech becomes slurred
What does 300mg/100ml of blood do?
Unconscious
Must be careful of choking on vomit if lying on back- falling/sleeping
What happens with 400mg/100ml of blood?
Death from respiratory failure, alcohol has hit brain stem
What is the movement of drugs called?
Pharmacokinetics
What is the highest level of blood alcohol ever seen?
628mg/100ml of blood
Where is alcohol rapidly absorbed?
Mouth
Lungs
Stomach
Small intestine
How much alcohol is absorbed by the stomach?
20%
Where is alcohol cleared from?
Predominantly by metabolism in the liver
Why does fizzy/gas alcohol get you more drunk faster?
Alcohol is inhaled into the lungs
What does alcohol metabolise to?
CH3CHO + NADH
As NAD+ added