Alcohol Flashcards

1
Q

Ethyl Alcohol structure is similar to?

A

CHO

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2
Q

Ethyl Alcohol metabolism is similar to?

A

Fat Metabolism

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3
Q

Ethyl Alcohol provides how many kcals/g?

A

7

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4
Q

Ethyl Alcohol’s absorption is ______ and transport is facilitated via what systemic pathway?

A

Fast Absorption
Transport > Circulatory System (water soluble)

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5
Q

What micronutrient can absorb alcohol?

A

Sodium

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6
Q

What are the two pathways for alcohol oxidation (metabolism)?

A

Alcohol Dehydrogenase Pathway (ADH)
Microsomal Ethanol Oxidizing System (MEOS)

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7
Q

The Alcohol Dehydrogenase Pathway (ADH) produces enzymes in the ______ & on a ______ basis?

A

Liver / Hourly Basis

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8
Q

The ADH pathway functions in the?

A

Cytoplasm

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9
Q

The ADH pathway requires?

A

NAD+

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10
Q

The ADH pathway has a _______ production capacity?

A

Fixed Hourly Production

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11
Q

The Microsomal Ethanol Oxidizing System (MEOS) produces more _____ as more _____ is absorbed?

A

Produces more enzymes the more ethanol is consumed

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12
Q

The MEOS pathway functions in the?

A

ER of the Mitochondria

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13
Q

The MEOS pathway requires what carriers?

A

FAD, FMN, Cytochrome P-450
(similar to ETS)

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14
Q

The MEOS oxidizes what concurrently?

A

NADPH

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15
Q

The MEOS is said to be a _____ system?

A

Trainable

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16
Q

When Alcohol is ingested it is treated as ____ and will do what to other glycolytic & oxidative pathways?

A

Treated as VIP > will shut down other metabolism pathways.

17
Q

The initial product of ethanol oxidation is _____ & is _____ toxic than alcohol, therefore requiring fast conversion.

A

Acetaldehyde > more toxic than alcohol.

18
Q

Too much acetaldehyde coming into contact with the liver will result in what?

A

Cirrhosis

19
Q

Too much alcohol intake will result in _____ NADH : NAD+ ratios?

A

High Ratios

20
Q

What mechanisms result in Fatty Liver from alcoholism?

A

Increased Fatty Acid Synthesis
Increased TG Synthesis

21
Q

Alcoholism impairs what metabolic pathway?

A

GNG

22
Q

Alcoholism results in vitamin A deficiency through what mechanism?

A

Retinol Dehydrogenase does not become activated

23
Q

Alcohol Intake can increase what?

A

HDL-C

24
Q

Alcohol Intake can decrease what?

A

Platelate Aggregation

25
Q

What is the RDA for women with alcohol?

A

no more than 1 drink/day

26
Q

What is the RDA for men with alcohol?

A

no more than 2 drink/day