AINES Flashcards

1
Q

Historia

A

Leroux, Sauce blanco o salix alba, salicina

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2
Q

Clasificacion

A
Salicilatos
Pirazolonas
Anilina
Ac propionico
Fenamato (antranilico)
Ac acetico
Coxibes
Otros
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3
Q

Clasificacion salicilatos

A

Ac salicilico

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4
Q

Clasificacion pirazolonas

A

Dipirona o metamizol

Butazonas

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5
Q

Clasificacion anilinas

A

Acetaminofen

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6
Q

Clasificacion ac propionico

A

Naproxeno

Iburoprofen

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7
Q

Clasificacion fenamatos (antranilico)

A

Ac mefenamico

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8
Q

Clasificacion ac acetico

A
Diclofenaco
Indometacina
Piroxicam
Meloxicam
Ketorolaco
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9
Q

Clasificacion coxibes

A

Celecoxib

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10
Q

Clasificacion otros

A

Nimesulide

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11
Q

Vm corta menor 4 hr

A
Paracetamol
Diclofenaco
Iburoprofeno
Metamizol o Dipirona
Tolmetina
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12
Q

Via parenteral

A

IV: metamizol
IM: metamizol, diclofenaco

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13
Q

Distribucion

A

Proteinas 90%

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14
Q

Biotransformacion

A
Oxidacion
Hidrolisis
Glucoronico
Glicina
Sulfato
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15
Q

Excrecion

A

Renal

Biliar

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16
Q

Acciones salicilatos

A
Analgesico
Antii
Antipiretico
Antirreuma
Antiagregante
17
Q

Analgesicos

A
Salicilatos
Pirazolonas
Anilina
Fenamato
Coxibes
Nimesulide
18
Q

Antipireticos

A
Salicilatos
Pirazolona
Anilina
Propionico
Nimesulide
19
Q

Antiagregantes

A

Salicilatos

20
Q

Antirreumaticos

A
Salicilatos
Butazona
Propionico
Ac acetico
Coxibes
21
Q

Analgesicos antipireticos y antiinflamatorios

A

Nimesulida y salicilatos

22
Q

Para el cierre del ductus arterioso

A

Ac acetico (indometacina)

23
Q

Formacion de ac araquidonico a partr de

A

Fosfolipidos de membrana por fosfolipasa

24
Q

COX que es

A

Prostaglandin sintetasa

25
Q

COX 2 selectivos

A

Celecoxib, meloxicam, nimesulide

26
Q

Propiedad antipiretica

A

Metamizol sudor y vasodilatación

Acetaminofen centro termorregulador hipotalamo

27
Q

Uricosuricos y antigotosos

A

Butazonas

Ac acetico

28
Q

Acciones tromboxanos

A

Vasoconstricción

Agregante

29
Q

Acciones prostaglandinas

A

Vasodilatador

Antiagregante

30
Q

Antiespasmodicos

A

Pirazolona metamizol

Fenamato

31
Q

Amenaza de parto prematuro

A

Ac acetico indometacina

32
Q

Dosis Acetaminofen

A

40 mg/kg/ dia

Repartido en 3

33
Q

Presentacion Acetaminofen

A

Gotas 100
Jarabe 120/5ml
Suposit 300
Tabs 500 y 750

34
Q

Salicilismo

A
Suicidio 
Sudoracion
Hipernea
Hipertermia
Alucinaciones
Convulsiones
Coma
35
Q

Tx salicilismo

A
Lavado
Temperatura
Liquidos
Vit k
Control Acido base
Transfusion
Dialisis