Aging Flashcards
How does genetic contribute to aging?
- 20% contribution to longevity
- DNA damage
- DNA repair capacity
External factors contribute (BLANK) % to longevity
80%
What are some environmental external factors that contribute to aging?
Exposure to:
- pollutants/ toxins
- Bacteria/ viruses
- Damage to nervous system
What are some lifestyle external factors that contribute to aging?
- Exercise
- Diet
- Stress
- Self efficacy (self limiting perspective)
What are some psychosocial external factors that contribute to aging?
- Social relationships
- Feelings of loneliness
- Quality of life
Exercise has been shown to improve?
- CV health & aerobic power
- Muscle strength & physical function
- Flexibility
- Control obesity
- Mental functions
- Improve biological age by 10-20 years
As we age what happens to our connective tissue?
- Altered ability to maintain & repair
- Decrease water concentration
- Collagen & elastin become more stiff and brittle
As we age what happens to our cartilage?
- Calcification
- Decrease water content
- Intervertebral discs shrink & crack (increase load on other structures)
As we age there are changes to connective tissue and cartilage, ultimately these changes lead to what?
- Decreased load and energy absorption
- Increased risk of injury
- Functional implications
What is sarcopenia and when does it occur?
- Sarcopenia: Loss of muscle strength and functional quality
- As we age 1-3% per year >50
What happens to skeletal muscle as we age?
- Sarcopenia
- Decrease in number and diameter of mm fibers
- Muscle fibers become fat or collagen
- Maximize reserve before loss of function
What happens to bone as we age?
- Decrease in subchondral bone
- Osteopenia
What is osteopenia?
Increased osteoclast activity and decreased osteoblast
What are the functional implications due to musculoskeletal changes with age?
- Loss of ROM
- Pain
- Postural management
- Decreased load tolerance and absorption
- Morbidity and mortality
Because of the functional implication due to changes of musculoskeletal system with aging what ultimately occurs?
- Increase risk of injury, falls & fx
- Increase in pain
- Decrease mobility, function & participation
What are some postural changes with aging?
- Forward head
- Thoracic kyphosis
As we age there are structural changes seen in the heart and vascular system what does this cause?
- Reduced contractility, valve dysfunction, fibrosis
- Decreased heart rate max (which not altered by exercise)
What are some cardiovascular changes with aging according to thoracic spine?
- Thorax is stiffer
- Increased kyphosis diminishing rib care mobility
Cardiovascular changes with age cause diminished elastic recoil of the lung causes what to happen?
- Decreased lung volume then less oxygen reaching tissues