Aggregation Flashcards

1
Q

What is the sexuality of C elegans?

A

Hermaphrodite

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2
Q

What is the sexuality of C elegans?

A

Hermaphrodite

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3
Q

Hoe do social feeders behave?

A

Aggregate on the margins of the disk

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4
Q

What are the characteristics of aggregation?

A

Clumping and bordering

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5
Q

What is the mutant form of the behaviour?

A

Social

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6
Q

What is npr-1?

A

Gene responsible for aggregation

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7
Q

With what human peptide is npr-1 related?

A

Neuropeptide Y

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8
Q

What changes in order to differenciate between solitary and social feeders naturally?

A

A change from valine to phenylalanine in npr-1?

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9
Q

What is the mechanism underlying aggregation?

A

Creb transcriptional activation by GPCR

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10
Q

What is CREB?

A

A transcription factor

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11
Q

What is CRE?

A

An enhancer

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12
Q

What will ablation of ASH and ADL do?

A

Transform social animals to solitary feeders

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13
Q

What type of receptors are both ASH and ADL?

A

Nociceptors

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14
Q

Where does pain come from?

A

E. coli consume the worms

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15
Q

Where is the polymorphism located?

A

On the inner side of the membrane

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16
Q

What type of synapse is it between ash and RMG?

A

Gap junction

17
Q

What type of synapse is it between ASH and AVA?

A

Chemical synapse

18
Q

How is RMG controlled?

A

If NPr-1 is activated it inhibits RMG and it doesn’t receive signals from ASH and ADL anymore