After midterm #2 - antipsychotics Flashcards
Schizophrenia (psychotic disorder) - 2 or more of the features.
DSM-5 Key Features that Define the Psychotic Disorders
Positive symptoms (3)
1) delusions (distortions of reality, misevaluations and erroneous conclusions, paranoia, grandeur)
2) hallucinations (auditory most common)
3) disorganized thinking (speech) - faulty logic and reasoning/word salad
schizo “split” phrenology “mid”
separation between thought, emotion, behaviour
Negative symptoms (the five As)
affect flattened: unresponsive or blunted emotional responses; immobile, unresponsive face
alogia: impoverished speech; brief, uncommunicative replies
abolition: inability to initate or participate in goal-directed activities
anhedonia: loss of ability to experience pressure
asociality: socially withdrawn
When symptoms appear
over 3-5 years, -ve first then +ve
Szhiz stats
1% of general population, men=women
biological/genetic predisposition
risk developing SZ depends on degree of relatedness to SZ
Higher concordance rate for MZ than DZ twins
Mutations on a number of chromosomes create vulnerability
Vulnerability depends on evnrionemtnal influences to promote expression of genes