After midterm #2 - antipsychotics Flashcards

1
Q

Schizophrenia (psychotic disorder) - 2 or more of the features.

A

DSM-5 Key Features that Define the Psychotic Disorders

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2
Q

Positive symptoms (3)

A

1) delusions (distortions of reality, misevaluations and erroneous conclusions, paranoia, grandeur)
2) hallucinations (auditory most common)
3) disorganized thinking (speech) - faulty logic and reasoning/word salad

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3
Q

schizo “split” phrenology “mid”

A

separation between thought, emotion, behaviour

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4
Q

Negative symptoms (the five As)

A

affect flattened: unresponsive or blunted emotional responses; immobile, unresponsive face

alogia: impoverished speech; brief, uncommunicative replies

abolition: inability to initate or participate in goal-directed activities

anhedonia: loss of ability to experience pressure

asociality: socially withdrawn

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5
Q

When symptoms appear

A

over 3-5 years, -ve first then +ve

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6
Q

Szhiz stats

A

1% of general population, men=women

biological/genetic predisposition

risk developing SZ depends on degree of relatedness to SZ

Higher concordance rate for MZ than DZ twins

Mutations on a number of chromosomes create vulnerability

Vulnerability depends on evnrionemtnal influences to promote expression of genes

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