african trypanosomaisis life cycle (trypanosoma brucei)

Question 1

Stage 1, tsetse fly stage

Answer 1

tsetse fly bites mammal and injects metacyclic trypomastigotes)

Question 2

stage 2, mammalian stage

Answer 2

injected metacyclic trypomastigotes transform into bloodstream trypomastigotes and are carried to other sites

Question 3

stage 3, mammalian stage

Answer 3

trypomastigotes multiply by binary fission in body fluids

Question 4

stage 4, mammalian stage

Answer 4

circulating trypomastigotes in blood during acute phase, undetectable in latent phase

Question 5

stage 5, fly stage

Answer 5

fly bites mammal and ingests bloodstream trypomastigotes

Question 6

stage 6, fly stage

Answer 6

bloodstream trypomastigotes transform into procyclic trypomastigotes in vector midgut, multiply by binary fission

Question 7

stage 7, fly stage

Answer 7

procyclic trypomastigotes leave the midgut and transform into epimastigotes

Question 8

stage 8, fly stage

Answer 8

epimastigotes multiply in salivary gland, then transform into metacylcic trypomastigotes

Question 9

reservoir hosts for this parasite

Answer 9

cattle and wild ungulates