Affective Disorders Flashcards

1
Q

What are mood disorders?

A
  • disorders of mental status and function, altered mood being the core feature
  • states of depression and elevated mood-mania
  • primary problem or consequence of other illness e.g. dementia
  • most common group of mental disorders
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2
Q

What is the ICD-10?

A

International Classification of Disease 10th Ed.- WHO

  • F30- manic episode
  • F31- bipolar affective disorder
  • F32- depressive episode
  • F33- recurrent depressive disorder
  • F34- persistant mood (affective) disorder
  • F38- other mood (affective) disorder
  • F39- unspecified mood (affective) disorder
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3
Q

What are the psychological symptoms of depressive illness?

A
  • change in mood
  • depression
  • anxiety
  • perplexity
  • anhedonia
  • change in thought content
  • guilt
  • hopelessness
  • worthlessness
  • neurotic symptomology
  • ideas of reference
  • delusions + hallucinations
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4
Q

What are the physical symptoms of depressive illness?

A
  • change in bodily function
  • sleep- fatigue
  • constipation
  • appetite- weight loss
  • libido
  • energy
  • pain
  • change in psychomotor functioning
  • agitation
  • retardation
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5
Q

What are the social symptoms of depressive illness?

A
  • loss of interests
  • irritability
  • apathy
  • withdrawal, loss of confidence, indecisive
  • loss of concentration, registration + memory
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6
Q

What is the ICD-10 criteria for depression?

A
  • ≥ 2 weeks
  • no hypomanic/manic episodes in lifetime
  • not result of; psychoactive substance, organic mental disorder
  • if psychotic symptoms/stupor = severe depression with psychotic symptoms
  • must exclude other psychotic conditions
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7
Q

What is the ICD-10 criteria for depression somatic syndrome?

A
  • anhedonia
  • lack of emotional reactions
  • wake 2 hrs before normal time
  • depression worse in morning
  • objective evidence of; psychomotor agitation/retardation
  • loss of appetite, weight loss
  • loss of labido
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8
Q

What is the ICD-10 criteria for mild depression?

A
  • general criteria
    • 2 or more of:
  • abnormal depressed mood, most of day, almost everyday, for 2 weeks, largely uninfluenced by circumstance
  • anhedonia
  • dec. energy/inc. fatigue
    • (to reach 4 added criteria):
  • dec. confidence/self esteem
  • guilt/self reproach
  • suicdal thoughts/behaviour
  • agitation/retardation
  • sleep disturbance
  • appetite change
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9
Q

What is the ICD-10 criteria for moderate depression?

A
  • general criteria
    • 2 or more of:
  • abnormal depressed mood, most of day, almost everyday, for 2 weeks, largely uninfluenced by circumstance
  • anhedonia
  • dec. energy/inc. fatigue
    • (to reach 6 added criteria):
  • dec. confidence/self esteem
  • guilt/self reproach
  • suicdal thoughts/behaviour
  • agitation/retardation
  • sleep disturbance
  • appetite change
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10
Q

What is the ICD-10 criteria for severe depression?

A
  • general criteria
    • 2 or more of:
  • abnormal depressed mood, most of day, almost everyday, for 2 weeks, largely uninfluenced by circumstance
  • anhedonia
  • dec. energy/inc. fatigue
    • (to reach 4 added criteria):
  • dec. confidence/self esteem
  • guilt/self reproach
  • suicdal thoughts/behaviour
  • agitation/retardation
  • sleep disturbance
  • appetite change
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11
Q

What are the differential daignoses for depression?

A
  • normal reaction to life event
  • SAD
  • dysthymia
  • cyclothymia
  • bipolar
  • stroke, tumour, dementia
  • hypothyroidism, Addison’s, hyperparathyroidism
  • influenza, glandular fever, hepatitis, HIV/AIDS
  • drugs
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12
Q

What are the different types of treatment for depression?

A
  • antidepressants
  • psychological treatment
  • CBT
  • IPT
  • indivdual dynamic psychotherapy
  • family therapy
  • physical treatments
  • ECT
  • psychosurgery
  • DBS
  • VNS
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13
Q

What are different tools for measuring depression?

A
  • SCID (Structured Clinical Interview for DSM disorders)
  • SCAN (schedules for Clinical Assessment in Neuropsychiatry)
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14
Q

What is mania?

A
  • feeling/mood from near-normal experience to life-threatening illness
  • similarities to mental affects of stimulant drugs
  • form of pathological innapropriate elevated mood
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15
Q

What are the ICD-10 categories of mania?

A
  • F30.0- hypomania
  • F30.1- mania without psychotic symptoms
  • F30.2- mania with psychotic symptoms
  • F30.8- other manic episode
  • F30.9- manic episode, unspecified
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16
Q

What is the ICD-10 criteria for hypomania?

A
  • lesser degree of mania, no psychosis
  • mild elevation of mood, several days
  • inc. energy, activity, feeling of wellbeing
  • inc. sociability, talking, overfamiliarity, sexual energy
  • dec. need for sleep
  • irritable
  • dec. conc, new interests, mild overspending
  • no severe disruption of work or social rejection
17
Q

What is the ICD-10 criteria for mania?

A
  • 1 week severe disruption to work and social
  • elevated mood, inc. energy, overactivity, pressure of speech
  • dec. need for sleep
  • disinhibition
  • grandiosity
  • altered senses
  • extravagant spending
  • irritable rather than elated
18
Q

What are the differential diagnoses for mania?

A
  • mixed affective state
  • schizoaffective disorder
  • schizophrenia
  • cyclothymia
  • ADHD
  • drugs, alcohol
  • stroke, MS, tumour, epilepsy, AIDS, neurosyphilis
  • Cushing’s, hyperthyroidism
  • SLE
19
Q

What are different tools for measuring mania?

A
  • SCID
  • SCAN
  • Young Mania Rating Scale (YMRS)
20
Q

What is the treatment for mania?

A
  • antipsychotics
  • olanzipine
  • risperidone
  • quetiapine
  • mood stabilisers
  • sodium valproate
  • lamotrigene
  • carbamazipine
  • lithium
  • ECT
21
Q

What are the ICD-10 categories of bipolar disorder?

A
  • F31.0- BAD, current hypomanic
  • F31.1- BAD, current manic without psychosis
  • F31.2- BAD, current manic with psychosis
  • F31.3- BAD, current mild/mod depression
  • F31.4- BAD, current severe depression without psychosis
  • F31.5- BAD, current severe depression with psychosis
  • F31.6- BAD, current episode mixed
  • F31.7- BAD, current episode in remission
  • F31.8- other bipolar affective disorders
  • F31.9- BAD, unspecified
22
Q

What is the ICD-10 criteria for bipolar affective disorder?

A
  • repeated (2+) episodes of depression and mania/hypomania