Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Derma > Afectiuni buloase > Flashcards

Afectiuni buloase Flashcards

1
Q

Care sunt afectiunile buloase cutanate?

A
  1. Penfigus vulgar
  2. Penfigoid bulos
  3. Porfiria cutanata tardiva
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Ce este PENFIGUSUL VULGAR?

A

Afectiunea autoimuna caracterizata prin autoanticorpi impotriva moleculeor de adeziune din epiderm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Prin ce se caracterizeaza PENFIGUSUL VULGAR ?

A

Autoanticorpi impotriva celulelor de adeziune din epiderm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Ce tip de pacient este afectat de PENFIGUSUL VULGAR?

A
  • varsta mijlocie

- varstnici

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

IE PENFIGUSUL VULGAR

A
  • bule dureroase, fragile, localizate in orofaringr, torace, fata si regiune perineal -> se rup usor si apar frecvent eroziuni si descuamari
  • semn NIKOLSKY +
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Semnul NIKOLSKY + este in?

A
  • Sdr STEVENS JOHNS

- PENFIGUSUL VULGAR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Unde sunt localizate bulele din PENFIGUSUL VULGAR?

A
  • orofaringe
  • torace
  • fata
  • reg perineala
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Examenul de laborator in PENFIGUSUL VULGAR

A

Biopsia cutanata

  • separatea celulelor epidermide ACANTOLIZA
  • MB intacta
  • imunoflorescenta -> autoanticorpi anti-epidermici
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Ce inseamna Acantoliza?

A

Separarea celulelor epidermice

- biopsie cutanata in PENFIGUSUL VULGAR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Biopsia cutanata in PENFIGUSUL VULGAR

A
  • separare celule epidermice ACANTOLIZA
  • MB intacta
  • imunoflorescenta -> anticorpi anti-epidermici
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Tratamentul in PENFIGUSUL VULGAR

A
  • CORTICOSTEROIZI
  • AZATIOPRINA
  • CICLOFOSFAMIDA
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Complicatii in PENFIGUSUL VULGAR

A
  • sepsis

- mortalitate crescuta in lipsta tratamentului

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Mortalitatea in PENFIGUSUL VULGAR

A

Crescuta in lipsa tratamentului

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Ce este PENFIGOIDUL BULOS?

A

Afesgtiune autoimuna caracterizata prin aparitia autoanticorpii impotriva MB a epidermului

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Prin ce se caracterizeaza PENFIGOIDUL BULOS?

A

Autoanticorpi impotriva MB a epidermului

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Ce fel de pcienti sunt afectati de PENFIGOIDUL BULOS?

A

> 65 ani

17
Q

IE PENFIGOIDUL BULOS?

A
  • bule diseminate in special pe suprafete flexoare si zona perineala
  • insotit de prurit
  • > se sparg bule si bezicule si apar eroziuni
  • dimensiuni mari
  • fond eritematos
  • semnul NIKOLSKY -
18
Q

Unde sunt diseminate bulele in PENFIGOIDUL BULOS?

A
  • suprafete flexoare

- zona perineala

19
Q

Examenul de laborator in PENFIGOIDUL BULOS?

A
  • imunofluorescenta - auto-anticorpi anti-MB
20
Q

Tratamentul in PENFIGOIDUL BULOS?

A
  • CORTICOSTEROIZI orali/topici

- AZATIOPRINA

21
Q

Ce inseamna PORFIRIA CUTANATA TARDIVA?

A

Boala determinata de deficitul de UROPORFINOGEN-DECARBOXILAZA hepatica -> enzima implicata in metabolismul hemului

22
Q

Ce este uroporfinogen-decarboxilaza?

A

Enzima hepatica implicata in metabolismul hemului

23
Q

Factori de risc in PORFIRIA CUTANATA TARDIVA

A
  • alcoolism
  • hepatita C
  • supraincarcare de hem
  • tratament cu estrogeni
  • fumat
24
Q

IE PORFIRIA CUTANATA TARDIVA?

A
  • leziuni buloase cronice, nedureroase, la nivelul teg expus la soare ( in special fata dorsala maini, antebrat, gat, fata, urechi, picioare ) -> daca se rup se vindeca greu, cu cicatrici
  • piele hiperpigmentata, hipertricoza
25
Q

Lozalizare frecventa PORFIRIA CUTANATA TARDIVA

A

Tegument expus la soare

  • fata dorsala maini
  • antebrat
  • gat
  • fata
  • urechi
  • picioare
26
Q

Examen de laborator in PORFIRIA CUTANATA TARDIVA

A 
\+++
ASAT/ALAT
Porfirina plasmatica
Porfirina urinara
- - -
Uroporfinogen-decarboxilaza hepatica
27
Q

Tratamentul in PORFIRIA CUTANATA TARDIVA?

A
  • FLEBOTOMIE periodica
  • CLOROCHINA sau HIDROCLOROCHINA in doze mici
  • creme cu SPF
  • evitare factori declansatori : expunere la soare, alcool, estrogeni, tutun, suplimente cu fier
28
Q

Factorii declansatori din PORFIRIA CUTANATA TARDIVA?

A
  • expunerea la soare
  • alcool
  • tutun
  • estrogeni
  • suplimente cu fier
29
Q

Ce afectiuni buloase se trateaza cu CORTICOSTEROIZI?

A
  • penfigus vulgar

- penfigoid bulos

30
Q

Ce afectiuni bulose cutanate se trateaza cu AZATIOPRINA?

A
  • penfigus vulgar

- penfigoid bulos

Derma (5 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions