Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

pulm > adverse effects > Flashcards

adverse effects Flashcards

1
Q

4 adverse effects of beta2 agonists

A
  1. decreased BP
  2. stimulation of heart: increased HR
  3. hyperglycemia
  4. hypokalemia: QT prolongation
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

adverse effects of theophylline/aminiophylline

A

same as beta agonists:

  1. increased BP
  2. heart stimulation
  3. hyperglycemia
  4. hypokalemia: QT prolongation
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

muscarinic antagonists

A
  • pupillary dilation and cycloplegia on contact with eye
  • urinary retention
  • dry mouth
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

glucocorticoids

A
  • oral candidiasis/immunosuppression
  • decreased growth rate/bone density
  • increased BP/weight
  • glucose intolerance
  • Cushingoid syndrome
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what are the distinct adverse effects of leukotriene antagonists

A

monteleukast: URT inflammation/infection

zafilukast/zileuton: increased hepatic enzymes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

hallucinations due to increased serotonin. what other drug increases serotonin?

A

dextromethorphan

-diphenhydramine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what are the adverse effects of diphenhydramine

A

anticholinergic adverse effects

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what drug always causes constipation? what are 2 other adverse effects

A

codeine

  • sedation
  • histamine release: hypotension
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

which drug causes uric acid nephrolithiasis?

A

guaifenesin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

which mucolytic can cause bronchospasm?

A

acteyl cysteine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what are 3 adverse effects of dornase alfa?

A
  • voice alteration
  • pharyngitis/laryngitis
  • conjunctivitis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what 2 major types of adverse effects do 1st gen antihistamines cause?

A
  1. anticholinergic effects

2. drowsiness/impaired alertness or cognition

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what two TB drugs cause peripheral neuropathy? how do you treat that? what other adverse effects do they cause?

A

isoniazid and ethionamide

  • give pyridoxine/B6 supplement
  • also hepatotoxicity
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what TB drug turns body fluids red-orange? what other adverse effect is it responsible for?

A

rifampin

-hepatotoxicity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what TB drug causes optic neuritis? how does that manifest? what other adverse effect does it cause?

A

ethambutol

  • diminished visual acuity and loss of color differentiation
  • also hyperuricemia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what TB drug causes nephrotoxicity (ATN)? what other adverse effects does it cause?

A

capreomycin

  • ototoxicity
  • eosinophilia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

what TB drug causes reversible CNS effects?

A

cycloserine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

what adverse effects is pyrazinamide responsible for?

A

hepatotoxicity and hyperuricemia

19
Q

which two antibiotics cause cholestatic jaundice?

A

azithromycin and erythromycin

20
Q

what are the two main adverse effects of doxycycline?

A

photosensitivity and decreased bone growth

21
Q

what antibiotic causes tendon rupture and cartilage damage in young kids?

A

levofloxacin

22
Q

what are 3 adverse effects of gentamicin?

A
  1. ototoxicity
  2. neuromuscular paralysis
  3. nephrotoxicity
23
Q

what 2 antibiotics cause QT prolongation

A

azithromycin and erythromycin

24
Q

what antibiotic causes decreased coagulation?

A

piperacillin

25
Q

what drug combination is used to prevent renal toxicity from the antibiotic in it?

A

imipenem/cilastin

26
Q

what antibiotic causes Red Man Syndrome? what other two adverse effects does it cause?

A

vancomycin

  • ototoxicity
  • nephrotoxicity
27
Q

what three antibiotics cause nephrotoxicity

A

impenem, gentamicin and vancomycin

28
Q

what is the big problem with zanamivir?

A

fatal bronchospasms in those with underlying lung disease

29
Q

which antiviral has black box warning for renal toxicity?

A

cidofovir

30
Q

which antiviral has black box warning for hemolytic anemia?

A

ribavirin

31
Q

what are the adverse effects of valacyclovir/acyclovir?

A

renal impairment: hydrate well

32
Q

what is the main adverse effect of amphotericin?

A

nephrotoxicity

33
Q

what is the main adverse effect of flucytosine?

A

hematotoxicity: anemia, blood dyscrasias

34
Q

what is the main adverse effect of rituximab?

A

HTN

35
Q

what are the 2 main adverse effects of azathioprine?

A
  1. thrombocytopenia/leukopenia

2. mutagenic/neoplastic

36
Q

hypotension and the need to monitor bleeding are adverse effects of what type of drugs?

A

prostanoids

37
Q

what are 2 toxicities of bosentan?

A

blood and liver

38
Q

what are 2 adverse effects of cisplatin?

A
  • dose-limiting nephrotoxicity

- ototoxicity

39
Q

what is the main adverse effect of gemcitabine?

A

peripheral neuropathy

40
Q

what 2 cytotoxic drugs cause increased hepatic enzymes

A

carboplatin and pemetrexed

41
Q

what has cumulative dose limiting cardiotoxicity

A

doxorubicin

42
Q

what cytotoxic drug has dose limiting hematologic toxicity?

A

etoposide

43
Q

what are two adverse effects of cyclophosphamide?

A

hemorrhagic cystitis and pulmonary fibrosis

pulm (7 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions