Adult Endocrinology Flashcards

1
Q

what are clinical presenting sx of DM

A
Polyuria
Polydypsia
Nocturia 
Blurred Vision 
Weight Loss
Infections/Slow healing
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2
Q

What is the diagnostic fasting glucose for a diabetic

A

> 126

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3
Q

What is the two hour plasma glucose levels following a 75g OGTT

A

> 200mg

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4
Q

What could be a cause of mental status changes in someone with DM

A

High or low blood sugar

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5
Q

Which hyperglycemic events are more likely in type 1 DM? Type 2?

A

Type 1 DKA

Type 2 is HHS

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6
Q

What main things lead to DKA

A
Inadequate Insulin administration
Infection
Infarction
Surgery 
certain drugs (cocaine)
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7
Q

what are initial symptoms of DKA

A
Anorexia
Nausea
Vomiting
Polyuria
Thirst
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8
Q

what symptoms indicated progression of DKA

A

Abdominal pain
Altered mental status
Coma

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9
Q

What type of acidosis would DKA illicit

A

High Anion gap

also metabolic but I didnt know how to ask High anion without giving it away. if you knew that rate 5 and be on your way

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10
Q

what would you monitor in the ICU for DKA

A

Acid-base status
Renal Function
Potassium and other electrolytes

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11
Q

what is the general 1-2-3 rule of fluid replacement

A

2-3 L NS over 1-3 hrs
1/2 saline at 150mL/hr
When glucose gets to 250 mg switch to D5 1/2 NS

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12
Q

What is the initial insulin regiment for DKA correction

A

10-20 units IV
then 5-10 units/hr continuous IV
increase if no response

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13
Q

What is important to evaluate about your patient with DKA

A

underlying cause! or else they will relapse

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14
Q

What electrolyte needs to be replaced in DKA

A

Potassium

keep an eye on cardiac function throughout

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15
Q

What are absent in NKHS (HHS) to differentiate it from DKA

A

absent N/V. abdominal pain, and kussmaul respirations

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16
Q

What is the major cause of mortality in T2DM

A

Cardiovascular disease

17
Q

What does an HbA1C tell you clinically (not what it is)

A

the 3-4 month average level of blood sugar.

Good for checking compliance

18
Q

What is a good way to evaluate nephropathy

A

Spot/random urine sample

-look for protein

19
Q

is 24 hr urine collection used often

A

no it can be cumbersome

but i think this is outpatient

20
Q

What should DM pts do daily

A

Foot inspection

21
Q

What should be the levels of TSH and Free T4 in primary hypothyroidism

A

TSH up

T4 down

22
Q

What should be the levels of TSH and Free T4 in primary hyperthyroidism

A

TSH down

T4 Up

23
Q

What is the temperature trend of thyroid nodules and how likely they are to malignant

A

Colder more malignant

24
Q

What should suspect if Calcium and phosphate are opposite

A

PTH issue

25
Q

What should you suspect if the calcium and phosphate do the same thing

A

Vit D issue

26
Q

what are the classifications of hypercalcemia

A
  1. parathyroid-related
  2. Malignancy-related
  3. Vit-D
  4. Associated high bone turnover
  5. Renal Failure
27
Q

what is the EKG finding of hypercalcemia

A

shortened QT interval