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01. Cardiopulm Renal > Adrenoreceptors > Flashcards

Adrenoreceptors Flashcards

1
Q

α1 receptor (G protein and effect)

A

Gq protein –> increase IP3 and DAG

common to all alpha 1

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2
Q

α2 receptor (G protein and effect)

A

Gi protein –> decrease cAMP

common to all alpha 2

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3
Q

β type receptor (G protein and effect)

A

Gs protein –> increase cAMP

common to all beta type

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4
Q

Dopamine D1 and D5 receptors (G protein and effect)

A

Gs protein –> increase cAMP

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5
Q

Dopamine D2, D3, D4 receptors

A

Gi protein –> decrease cAMP

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6
Q

α1 receptor action on most vascular smooth muscle

A

contraction

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7
Q

α1 receptor action of pupillary dilator muscle

A

contraction (dilates pupils)

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8
Q

α1 receptor action on prostate

A

contraction

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9
Q

α1 receptor action on heart

A

increases force of contraction

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10
Q

α2 receptor action on platelets

A

aggregation

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11
Q

α2 receptor action on adrenergic and cholinergic nerve terminals

A

inhibits neurotransmitter release

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12
Q

α2 receptor action on some vascular smooth muscle

A

contraction

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13
Q

α2 receptor action on fat cells

A

inhibits lipolysis

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14
Q

β1 receptor action on heart

A

increases force and rate of contraction

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15
Q

β1 receptor action on juxtaglomerular cells

A

increases renin release

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16
Q

β2 receptor action on respiratory, uterine and vascular smooth muscle

A

promotes smooth muscle relaxation

17
Q

β2 receptor action on skeletal muscle

A

promotes potassium uptake

18
Q

β2 receptor action on human liver

A

activates glycogenolysis and gluconeogenesis

19
Q

β3 receptor action on bladder

A

relaxes detrusor muscle

20
Q

β3 receptor action on fat cells

A

activates lipolysis

21
Q

D1 action on smooth muscle

A

dilates renal blood vessels

22
Q

D2 action on nerve endings

A

modulates transmitter release

01. Cardiopulm Renal (9 decks)

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