Adrenergic Antagonists Flashcards

1
Q

non selective alpha blockers

A

phenoxybenzamine

phentolamine

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2
Q

blocks A1 and A2 causing increase of NE that then stimulates beta receptors
treatment for HTN in pheochromocytoma

A

phenoxybenzamine

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3
Q

block A1 and A2 causing reflex stimulation of SANS due to hypotension cause tachycardia
used to treat pheochromocytoma

A

phentolamine

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4
Q

selective A1 blockers

A

prazosin
terazosin
doxazosin
tamsulosin

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5
Q

A1a inactivation: relaxation of bladder trigone, prostate, urethra - increase urinary outflow, complete emptying of bladder

A

selective A1 blockers

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6
Q

used to treat essential HTN

A

prazosin
terazosin
doxazosin

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7
Q

patient loses consciousness 30-60 minutes after 1st dose > result severe postural hypotension > avoid driving and hazardous activity. admin initial dose at bed time

A

1st dose effect

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8
Q

used to treat BPH and given with finasteride

A

tamsulosin

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9
Q

selective A2 blcokers

A

yohimbine

mirtazapine

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10
Q

increase NE
aphrodisiac
SE: HTN

A

yohimbine

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11
Q

increase NE
depression
SE: increase NE at synaptic cleft in CNS

A

mirtazapine

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12
Q

non selective beta blockers

A
propranolol
sotalol
timolol
carteolol with ISA
nadolol
penbutolol with ISA
pindolol with ISA
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13
Q

decreases HR, CO, renin, insulin, aqueous humor secretion

causes vasoconstriction and fall in BP

A

propranolol

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14
Q

used to treat HTN, angina cardiac arrhythmias, CHF, MI, used to depress sympathetic - essential tremors, hyperthyroidism, stage fright, migraine and glaucome

A

propranolol

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15
Q

antidote for beta blockers overdose increase AC - increase cAMP; has inotropic and chronotropic effects o heart

A

glucagon

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16
Q

K blocker, prevents re polarization, prolongs potentials

A

sotalol

17
Q

used to treat glaucoma

dont give to diabetics

A

timolol

18
Q

selective cardio B1 blockers

A
betaxolol
bisoprolol
esmolol
atenolol
metoprolol
acebutolol with ISA
nebivolol
19
Q

alpha and beta blockers

A

carvedilol

labetalol with ISA

20
Q

drug of choice with HTN emergency

A

labetalol