Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharm Block 1 > Adrenergic Agonists > Flashcards

Adrenergic Agonists Flashcards

1
Q

inhibits tyrosine hydroxylase

A

metyrosine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

inhibits VMAT

A

reserpine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

inhibits NET

A

cocaine

TCAs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

inhibit VAMPS and SNAPS

A

bretylium

guanethidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q 
B1 = B2
vasodilator, increased CO 
decreased DAP and MAP
tx: bronchospasm, HB, Brady arrhythmias
SE: flush, angina, arrhythmias
A

isoproterenol - nonselective

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

A1, A2, B1
increases TPR, DAP, SAP
+ inotropic effects on heart

A

NE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

used in cardiac arrest

hypotension

A

NE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

ADR: anxiety, palpitation, acute rise BP, headache, necrosis, gangrene, contracts uterus, severe HTN, anginal pain

A

NE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

A1, A2, B1, B2

.3 - .5 ml per 1:1000

A

Epi

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

low dose: decrease TPR, DAP, MAP
medium dose: increase SBP, DAP decrease, no change MAP and no reflex HR change
high dose: vasoconstriction- MAP increase, SAP increase, DBP decrease, increase HR and decrease reflex HR

A

Epi

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

ADR: restlessness, throbbing headache, tremor, cerebral hemorrhage, cardiac arrhythmias

A

Epi

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Contraindicated: hypertensives, hyperthyroid, and angina pectoris, MAOI use

A

Epi

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

A1, A2, B1, B2
gains access to CNS
pseudoephedrine - OTC decongestant - cold meds
displaces NE from vesicle

A

ephedrine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

increase urine output

D1

A

dopamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

D1
peripheral arterial dilation and naturiuresis
treats HTN - increases salt and water excretion
SE: reflex tachycardia, flush, headache, increases IOP
Contraindicated: glaucoma

A

fenoldopam

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

increases release of NE

Contraindicated in patients on MAOIs - cheese rxn

A

tyramine

17
Q

increase release of NE
enters CNS
SE: anorexia, euphoria, insomnia

A 
Amphetamines 
dextroamphetamines 
methylphenidate
modifinil
Methamphetamines
18
Q

treats ADHD

A

methylphenidate

19
Q

treats narcolepsy

A

modifinil

20
Q

inhibits dopamine re uptake

SE: HTN, stroke, bug crawling feeling

A

cocaine

21
Q

Direct acting A1 agonists

A

phenylephrine
methoxamine
oxymetazoline
xylometazoline

22
Q

increases BP, TPR, reflex bradycardia

A1a agonist - urinary continence

A

direct acting A1 agonists

23
Q

used to treat nasal contestant and mydriasis without cycloplegia

A

phenylephrine

24
Q

tretas paroxysomal atrial tachycardia

A

methoxamine

25
Q

used to treat topical decongestants because of their ability to promote constriction of nasal mucosal arteriole
Continuous use: increase BP, HTN, destruction of nasal muscose

A

oxymetazoline

xylometazoline

26
Q

after 3 days of use: A1 - desensitized (tachyphylaxis) - loss response; B2 - dominates, causing vasodilation and rebound nasal congestion occurs

A

rebound nasal congestion

27
Q

Direct acting A2 agonists

A

clonidine
methyldopa
apraclodidine
brimonidine

28
Q

decrease cAMP and Ca inflow; blocks release NE

A

clonidine

methyldopa

29
Q

used to treat HTN, diabetic diarrhea, narcotic addicts and to benzodiazepine withdrawal effects

A

clonidine

30
Q

SE: postural hypotension, dry mouth, sedation, rebound HTN

A

clonidine

31
Q

acts like pre synaptic A2 agonist: aqueous synthesis decrease; post synaptic A2 agonist: duct peristalsis - increase outflow
treats glaucoma

A

apraclodidine

brimonidine

32
Q

Direct acting B1 agonists

A

dobutamine

33
Q

Gs action
increases HR, SV, CO, BP, contractility
used to treat: heart failure, septic and cardiac shock
SE: tachycardia, HTN, angina, fatal arrhythmia

A

dobutamine

34
Q

Direct acting B2 agonists

A 
albuterol 
salmeterol
metaproterenol
ritodrine
terbutaline
35
Q

Gs action
decrease TPR and BP and bronchodilation
used to treat: bronchial asthma, B2 in bladder wall mediate relaxation - retention

A

albuterol
salmeterol
metaproterenol

36
Q

Gs action
decrease TPR and BP and bronchodilation
used to treat premature uterine contraction -

A

ritodrine

Pharm Block 1 (5 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions