Adrenergic Agents Flashcards
Beta-2 receptors
Cause relaxation of smooth muscle. Only epinephrine has activity at beta-2. It causes bronchodilation urinary storage and vasodilation
Alpha-1 receptors
Excitatory. Because contraction of smooth muscle everywhere but the G.I. system. Norepinephrine and epinephrine
What happens if you stimulate alpha-1
Smooth muscle contraction eXcept GI SMOOTH muscle cells
What happens if you stimulate beta-2
Smooth muscle relaxation
beta-1
Only excitatory cardiac effects
Talk about beta-1 FX at SA, AV node and ventricular cells
SA increase heart rate. AV increase speed of conduction. Ventricular increase contractility
Norepinephrine and epinephrine stimulation for alpha one, beta-1, beta-2
Epinephrine and norepinephrine stimulate alpha-1 and beta-1 about equally. Norepinephrine has little effect at beta-2. Epinephrine very powerfully stimulates beta-2!!!!