Adrenaline

Question 1

Adrenaline Presentation

Answer 1

1mg in 1ml (1:1000)

Question 2

Adrenaline Use

Answer 2

Anaphylaxis Life-threatening asthma Severe croup Cardiac Arrest Post ROSC .

Question 3

Adrenaline Type

Answer 3

A naturally occurring sympathomimetic agent

Question 4

Adrenaline Dose

Answer 4

Cardiac Arrest Adult: 1mg IV/IO every 3-5 minutes Paediatric / Newborn: Dilute 1mg adrenaline in 9ml normal saline (1000 mcg in 10mls, 1:10,000) 10mcg/kg = 0.1ml/kg (1:10000) every 3-5 minutes. Post ROSC Dilute 1mg Adrenaline in 9ml normal saline (1000 mcg in 10mls, 1:10,000) Adult: 50 mcg (0.5ml) every 3-5 min as required to maintain systolic blood pressure >90mmHg Paediatric: 1mcg/kg every 3-5 min (max bolus 50mcg) to maintain systolic blood pressure > 80 mmHg Titrate Adrenaline as required, to achieve and / or maintain the SBP requirements as listed above. Anaphylaxis or life-threatening Asthma Adult: 0.5mg IM into lateral mid-thigh (0.5ml of 1:1000), repeat every 5 minutes as clinically required Pregnant Females experiencing anaphylaxis: 0.3mg IM into lateral mid-thigh (0.3ml of 1:1000), repeat every 5 minutes as clinically required Paediatric: 0.01mg/kg IM into lateral mid-thigh, repeat every 5 minutes as clinically required Croup Infants/Paediatric: 5mg in 5mls nebulised once only. .

Question 5

Adrenaline Actions

Answer 5

Causes peripheral vasoconstriction Stimulation of cardiac conduction system causes increased contractions Causes bronchodilation and dilation of blood vessels in muscles .IV/IO: Onset 30 seconds, peak 3-5 minutes, duration 5-10 minutes IM: Onset 30-90 seconds, peak 5-10 minutes, duration 5-10 minutes

Question 6

Adrenaline Contraindications

Answer 6

There are no absolute contraindications for adrenaline.

Question 7

Adrenaline Adverse effects

Answer 7

Dysrhythmias Hypertension Pupil dilation Tremor Anxiety Palpitations .

Question 8

Adrenaline Precautions

Answer 8

Ischaemic Heart Disease Do not walk patient pre/post IM adrenaline administration in anaphylaxis .