Adrenal Gland Disorders

Question 1

Zones of the adrenal gland

Answer 1

Mineralocortocoids made in Zona Glomerulosa (Salt)
Glucocorticoids in the Zona Fasciculata (Sugar)
Androgens in the Zona Reticularis (Sex)
Gets Sweeter the deeper you go.
Catecholamines made in the Medulla.

Question 2

Adrenal Causes of Hypertension

Answer 2

Cushing’s (Hypercortisolism)
Conn’s (Hyperaldosteronism)
Pheochromocytoma

These causes of hypertension are curable with surgery.

Question 3

Clinical Presentation associated with Conn’s Syndrome

Answer 3

Hyperaldosteronism characterized by HTN, HYPOkalemia, and MEtabolic Alkalosis.

Question 4

Therapy for PRimary Hyperaldosteronism

Answer 4

Spironolactone…aldosterone antagonist that is also a potassium sparing diuretic (may cause gynecomastia)

Surgical resection used in a unilateral adenoma.

Question 5

Common name for Primary Adrenal Insufficiency

Answer 5

Addison’s Disease