adrenal gland 1

Question 1

how is adrenal corticosteroid production regulated ?

Answer 1

cortisol and androgen production are regulated by hormones produced by hypothalamus and anterior pituitary gland

aldosterone regulated by renin-angiotensin system and plasma potassium

Question 2

what is the main function of the renin-angiotensin system

Answer 2

it is the major regulator of aldosterone production

Question 3

when is the renin-angiotensin system activated

Answer 3

it is activated in response to a decrease in blood pressure

Question 4

what happens after the renin-angiotensin system is activated

Answer 4

leads to production of Ang II which causes direct (vasoconstriction) and indirect (aldosterone) methods of BP elevation

Question 5

what is the mechanism of action of corticosteroids

Answer 5

bind intracellular receptors
receptor/ligand complex binds DNA to affect transcription

Question 6

what are the 6 classes of steroid receptor

Answer 6

glucocorticoid
mineralocorticoid
progestin
oestrogen
androgen
vitamin D