ADR Management

Question 1

Deutetrabenazine/Austedo

Answer 1

Start at 6mg BID
Or- can try 12mg QHS
Above 12 mg per day, need BID dosing
Max 48 mg/day

Question 2

Benztropine/Cogentin

Answer 2

Dose range 2 to 8 mg per day
Start at 4 mg qd or BID

Question 3

Artane/trihexyphenidyl

Answer 3

5 to 15 mg per day usually
Take with meals to reduce incidence of ADRs
Try to wean off 1 to 2 weeks after starting an antipsychotic- DIP isn’t forever usually