ADME: Drugs Flashcards

1
Q

DMSO

A

enhances percutaneous absorption of many drugs, but is toxic

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2
Q

cimetidine

A

inhibits cytochrome P450 (CYP3A, CYP 2D6, CYP1A2), anti-ulcer drug

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3
Q

phenobarbial (barbiturates)

A

induce CYP IIb family

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4
Q

probenecid:

A

competitively inhibits renal tubular secretion of penicillin

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5
Q

penecillin

A

antibiotics

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