Adipose Flashcards
type of connective tissue in which fat storing cells (adipocytes) predominates; fills space between tissues to keep organs in place
adipose tissue
modified support cells specialized in the storage and metabolism of fat
adipocytes
what receptors are in adipocytes?
insulin, glucocorticoids, growth hormone, and noradrenaline
where are adipocytes derived?
mesenchyme
recognizable precursor of adipocytes are?
lipoblast
how are fats stored?
triacyl glyceride/triglycerides
differentiates into preadipocytes and fibroblast
mesenchymal cells
unilocular with one large lipid droplet occupying most of the cytoplasm; accumulates at 14th week age of gestation
white adipocytes
preadipocytes in the paraxial differentiates into?
brown adipocytes
appears as cluster of multilocular cells in white adipose tissue; amount and activity is higher in lean individual; increases in cold adaptation
brown adipocyte
used for triglyceride storage and mobilization; serves as structural fill; acts as thermal insulator under the skin, forms part of shock-absorbing padding; forms felxible and deformable cushion against compression
white adipose tissue
found particularly in newborn and some hibernating animals
brown adipose tissue
how many percent of a newborn’s body weight located in the back, neck and shoulders are the brown adipose tissue?
2-5%
what does the mitochondrial metabolism release instead of ATP?
heat
responsible for thermogenesis
brown adipose tissue
accumulation of adipose tissue that is of sufficient magnitude to impair health
obesity
what is the normal bmi range
18.5-25
what is the overweight bmi range?
25-29.9
“appetite suppressor”
leptin
too many leptin results to?
leptin resistant
what are the factors that decreases leptin?
sleep deprivation, stress, and inflammatory food
appetite stimulator
ghrelin
produced in stomach and is the only known gut hormone that increases food intake
ghrelin
factors that increases ghrelin?
sleep deprivation, stress, and inflammatory food increase
produced by adipose tissue; fat burning molecule; guardian against obesity
adiponectin
relatively large particles formed in the intestinal epithelial cells that are rich in ingested lipids
chylomicrons
target cell of leptin is found in the?
hypothalamus
