adipokines and gi hormones Flashcards
Adiponectin
Adipokine
Good
Inverse relationship with fat
Enhance sensitivity to insulin, anti-inflammatory, protect from arteriosclerosis
Lepton
Adipokine
Good
Increase with more fat
Obese are leptin resistant, tells body we are full
Works with adiponectin to increase insulin sensitivity, degrease TGs, inhibit fat accumulation
Angiopoietin-related protein
Adipokine
Insulin resistance, inflammatory response
Angiotensinogen
Adipokine
Increase BP, inflammation, insulin resistance, lipogenesis
Retinol binding protein
Adipokine
Insulin resistance in muscles
IL-g and TNF-alpha
Adipokine
Biomarkers for inflammation
Ghrelin
GI hormone
Decrease in obese
Stimulate hunger, control gastric motility and acid secretion, stimulate GH
GLP-1
GI hormone
Decrease in obese
Stimulate insulin secretion, inhibit glucagon release, slows gastric emptying, increase satiety
Peptide YY
GI hormone
Decrease in obese
Decrease appetite, inhibit gastric motility, increase energy expenditure
Cholecystokinin CCK
GI hormone
Decrease in obese
Increase satiety, decrease food intake, stimulate gallbladder contraction, pancreatic enzyme release, slow gastric emptying