Adipocytes & Obesity Flashcards
Adipose tissue is a type of ___ CT. The two types and their functions in 1 word are: _____ and _____.
Loose
White (energy)
Brown (heat)
White adipocytes Store energy in: Obesity or anti-obesity: Low or high mitochondria: Receptors for:
Large lipid droplets
Obesity
Low
Insulin, hormones, NA
Brown adipocytes
Store energy in:
Obesity or anti-obesity:
Low or high mitochondria:
Brown adipocytes
Store energy in: small lipid droplets
Obesity or anti-obesity: anti
Low or high mitochondria: high
Shivering is produced by oxidizing ____. It’s efficient/not.
Carbs and lipids
Not
BAT has more of the protein _____. Protons can _____ allowing _____. This can/can’t occur in plants
UCP1
flow through
Energy to be released as heat
Can
More DNP —> more/less energy —> high/low metabolic rate —> more/less fat burned to compensate
Less
High
More
Imaging technology to detect BAT
Metabolic info detected by:
Structural info detected by:
PET
CT
2 types of adult bat
Classic
Beige
Classic BAT
Found in:
Size compared to beige:
Size of lipid droplets:
Vascular places around middle of body + shoulders area
Smaller
Small
Beige BAT
Forms from ____ after stimulation of ____ by ____.
Found with ___ tissue.
____ gives it beige colour
WAT SNS NA WAT More lipid droplets and some mito
Browning of WAT occurs by ____ and whiting occurs by ___
Cold, B3 receptor
High fat diet
What is required for hot and cold therapy? And it turns __ to ___ tissue
Capsinoids, cold, high fat diet
White
Beige
Cachexia symptoms: ____, ____ loss, atrophy of _____ and ____. Can occur in ___ or other diseases. Browning Caused by hormone(?) _____ which makes ___ gland release ___.
Inflammation Body weight loss Adipose tissue and muscle Cancer IL-6 Adrenal NA
Does burning or cold produce more browning?
Burning
Is artificial WAT to BAT useful in humans and why?
Not really, only a small change in ATP usage and BAT activity. No browning
