ADHD drugs Flashcards

1
Q

Methylphenidate release

A

short
intermediate
long

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2
Q

DexMethylphenidate

A

short

long term

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3
Q

dextroamphetamine

A

short

intermediate

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4
Q

amphetamine-dextroamphetamine

A

short

long

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5
Q

lisdexaampthetamine

A

long

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6
Q

what is methylphendiate’s MOA

A

block reuptake of NE and dopamine

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7
Q

what is amphetamine’s MOA

A

promote NE and dopamine release

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8
Q

short acting brand names

A

ritalin
focalin
dexadrine
adderall

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9
Q

lisdezamphetamine brand name

A

vyvanse

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10
Q

unlabeled use of stimulants

A

depression

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11
Q

2ndary labeled use of vyvanse

A

binge-eating disorders

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12
Q

what drugs should you not combine stimulants with?

A
Anti-HTN
MAOI
linezolid
sympathomemetics
caffiene
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13
Q

ADR of stimulants

A
anorexia
sleep disturbance
tics
slow growth rate
lower seizure threshold
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14
Q

dosing regimen for stimulants

A

low and slow

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15
Q

who should we be careful about using stimulants in?

A

mania
psychosis
drug dependent ppl
ETOH dependent ppl

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16
Q

what should you monitor with stimulant use?

A
BP
pulse
S and S of depression, aggression, hostility
growth rate
signs of CNS stimulation
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17
Q

who needs an ECG before stimulant use?

A

ppl w/ pre-existing heart disease, FH, or arryhtmia

18
Q

what pts shouldn’t get stimulants

A
anxious pts
glaucoma pts
underlying cardiac dz pts
hyperthyroid pts
pts with tics
19
Q

what 3 drugs are used in ADHD that are NOT stimulants

A

Atomexetine
Guanfacine
Clonidine

20
Q

atomoxetine MOA

A

SNRI

21
Q

what should you not use atomoxtine with?

A

MAOI

linezolid

22
Q

atomoxetine ADR

A
Suidicality
HA
insomnia
Xerostomia
N/V
23
Q

when should atomoxetine be dosed?

A

@ night

24
Q

what should be monitored with atomoxetine use?

A
BP
HR
Growth
ADHD symptoms
worsening agression
25
Q

Guanfacine MOA

A

selective alpha 2 adrenergic agonist

26
Q

Guanfacine shouldn’t be used w/ what other drugs

A

Anti-HTN
vasodilators (PDE5)
CNS depressants

27
Q

Guanfacine ADRs

A

somnolence

hypotension

28
Q

who is Guanfacine good for?

A

pts that can’t use stimulants aka kids w/ tics

29
Q

Clonidine MOA

A

non-selective alpha 2 adrenergic agonist

30
Q

Clonidine shouldn’t be used w/ what other drugs?

A

CNS depressants
CCB and BB
Anti-HTN
Vasodilators

31
Q

Clonidine ADRs

A

sedation*****

irritability, emotionally flat, insomnia, withdrawl

32
Q

what are clinical signs of true ADHD

A

appears in 2 + settings

significant impairment in function

33
Q

tx for preschoolers

A

behaivor

34
Q

tx for kids 6-17

A

behavior + meds

35
Q

adderall (generic name)

A

amphetamine+ dextroamphetamine

36
Q

ritalin or methylin (generic name)

A

methylphnidate

37
Q

Focalin (generic name)

A

dexamethylphenidate

38
Q

how long do short-acting drugs take

A

3-4hrs

39
Q

how long do intermediate drugs take

A

6-10hrs

40
Q

how long do long release drugs take

A

8-12 hrs

41
Q

most commonly used drugs are what length?

A

long acting

42
Q

Dexadrine or procentra (generic name)

A

dextroamphetamine