ADHD Flashcards

1
Q

What is ADHD?

A

Attention Deficit/Hyperactivity Disorder (ADHD) is classified as a developmental disorder in the DSM-5
It is a persistent pattern of inattention and/or hyperactivity impulsivity

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2
Q

How many types of ADHD are there and what are they?

A

There are 3 types of ADHD.
- Inattentive type
- Hyperactive/Impulsive type
-Combined type

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3
Q

What are the diagnostic symptoms of the inattentive type?

A

-Often distracted
-Has problems staying focused
-Does not seem to listen
-Does not follow through on instructions
-Has problems organizing tasks and work
-Avoids or dislikes tasks that require sustained mental effort
-Often loses things
-Doesn’t pay close attention or makes careless mistakes
-Forgets daily tasks

Need 6/9 symptoms to diagnose

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4
Q

What are the diagnostic symptoms for the hyperactive/impulsive type?

A

-Fidgets with or taps hands or feet and squirms in seat
-Not able to stay seated
-Runs about or climbs where it is inappropriate
-Unable to play quietly
-Always “on the go”
-Talks too much
-Blurts out an answer
-Interrupts or intrudes on others
-Has difficulty waiting for their turn

Need 6/9 symptoms to diagnose

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5
Q

What are the diagnostic symptoms for the combined type?

A

6/9 symptoms from inattentive symptoms + 6/9 hyperactive/impulsive symptoms

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6
Q

Where must ADHD appear?

A

ADHD cannot only appear in 1 place but it has to appear in multiple places

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7
Q

What makes ADHD hard to diagnose?

A

Signs of the disorder may be minimal or absent when the individual is under close supervision, receiving frequent rewards for good behaviour, in a novel setting, or doing something interesting

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8
Q

What are some problems that may be created by ADHD?

A

Academic performance tends to suffer and social rejection is common

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9
Q

What is the prevalence of ADHD?

A

It is approximately 7.2% and male to female ratio is about 3:1, Adult ADHD prevalence is around 2.5%

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10
Q

What is the comorbidity rate of ADHD?

A

Only 1/3 of children are diagnosed with only ADHD, meaning 2/3 are diagnosed with atleast one other DSM disorder

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11
Q

What makes ADHD one of the most heritable disorders?

A

The etiology of ADHD has been suggested to be up to 80% genetics.

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12
Q

What is perinatal hypoxia?

A

A temporary shortage of oxygen around the time of birth, it has been linked to the development of ADHD

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13
Q

What does the “Go, No-Go” task show?

A

Untreated individuals with ADHD make more errors of commission and errors of omission

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14
Q

What does the Iowa Gambling task show?

A

Untreated individuals with ADHD are more likely to pick from the ‘risky’ deck

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15
Q

What is the difference in reward influence in children with ADHD vs children without ADHD and what does it point to?

A

Rewards have less of an influence over the behaviour of children with ADHD, this deficit points to issues with either executive function (frontal lobe) or reward function (mesocorticolimbic dopamine system)

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16
Q

What is the Dual Pathway Model?

A

It is a theory about ADHD that suggest dysfunctions in both the frontal lobe and mesocorticolimbic system are to blame in lack of reward influence in children behaviour

17
Q

What is the Alerting Network?

A

It includes the frontal cortex, the parietal cortex, and the thalamus, together they support attention. The alerting network is weaker in individuals with ADHD

18
Q

What is the Frontostriatal Circuit?

A

It includes the ventral anterior cingulate cortex, dorsal anterior cingulate cortex, nucleus accumbens, putamen, and the caudate nucleus. The ventral anterior cingulate and the dorsal anterior cingulate cortex control affective and cognitive components of executive control.

19
Q

What happens to the Frontostriatal Circuit in individuals with ADHD?

A

There are abnormalities with extend to the amygdala and cerebellum

20
Q

What is the most pharmacological treatment for ADHD?

A

Psychostimulant drugs such as methylphenidate (Ritalin/Concerta), amphetamine (Adderall), and d-amphetamine (Dexedrine)

21
Q

How does ADHD medication work?

A

Usually the dopamine transporters would move unbound dopamine from the synapse back to the sending neuron.
ADHD medication (Ritalin and even cocaine) block the dopamine transporters that move unbound dopamine back to pre synaptic neuron, causing dopamine to build up in the synapse.