Adenylyl Cyclase Pathway

Question 0

Second step

Answer 0

The receptor ligand complex activates Gs

Gs binds to adenylyl Cyclase (effector enzyme) and activates it by allosterically inducing a conformational change at its active site

Adenylyl Cyclase is an integral membrane enzyme whose active site faces the cytosol.

Question 1

First step

Answer 1

Hormone binds to a stimulators receptor.

Receptor undergoes conformational change

This promotes interaction between the receptor and stimulators G protein Gs

Question 2

Third step

Answer 2

Adenylyl Cyclase catalyze a the formation of cAMP from ATP