Adenosine

Question 1

Adenosine (Adenocard)

Class?

Answer 1

Antiarrhythmic

Question 2

Adenosine (Adenocard)

Action?

Answer 2

• Slow electrical conduction through AV node, and interrupts re-entry pathway, converting SVT to NSR
• ONSET= within 30 seconds DURATION= 1-2 minutes

Question 3

Adenosine (Adenocard)

Indications?

Answer 3

Indications: Dysrythmias (S-127, S-163)

-SVT: Supraventricular Tachycardia

Question 4

Adenosine (Adenocard)

Dosage / Route?

Answer 4

Dosage/Route:

Adult: 6mg rapid IV/IO; follow with rapid 20ml NS 12mg rapid IV/IO; follow with rapid 20ml NS If no sustained rhythm changes MR x1 in 1-2”

If patient has bronchospasm or COPD: Dosing as above per BHO

PEDS: PDC rapid IV BHPO: Follow each dose with rapid 20ml NS If no sustained rythm changes MR x1 BHPO

Question 5

Adenosine (Adenocard)

Contraindications:

Answer 5

• 2nd and 3rd degree AV heart blocks
• Sick sinus syndrome (without pacemaker)

Question 6

Adenosine (Adenocard)

SIDE EFFECTS:

Answer 6

• SOB/ dyspnea; may cause bronchospasm in COPD patients (BHO)
• Chest pressure/ palpitations
• Facial flushing/ headache
• Dizzy/ lightheadedness
• Nausea
• Transient arrhythmias (PVC’s, PAC’s, sinus bradycardia, AV block, sinus tach or a systole). These are generally not treated and are quickly self-limiting.

Question 7

Adenosine (Adenocard)

SPECIAL INFORMATION:

Answer 7

1. The half life of Adenosine is < 10 Seconds: Use large bore IV in large proximal Vein to assist administration of rapid (Within in 1 to 2 seconds) IV push.
2. Inject in IV port closest to patient and immediately follow with NS Flush using 20-ml syringe.
3. Obtain ECG documentation before, during, and after admininsitration.
4. Adensine does not convert AFib/AFlutter a transient modest slowing of ventricular response may occure. Obtain a 12 lead EKG prior to administration if AFIB/AFlutter is suspected.
5. Antagonized by caffine and theopylline. Adenosine may be ineffective or larger doses may be required.
6. 3rd dose is not indicated if patient has had a sustained rythm change following the 2nd dose.
7. If SVT patient is unstable or rythm refractory to treatment; cardioversion is treatment of choice.