Adenosine

Question 1

Adenosine Mechanism of Action

Answer 1

Activates Potassium Efflux Channels that hyperpolarizes the membrane and shorten the AP and decreases Force of Contraction in Nodal cells

Question 2

Adenosine Contraindications

Answer 2

• Accessory Pathway (e.g. WPW)
• Asthma or severe COPD (may cause bronchoconstriction)
• Sick Sinus Syndrome
• Broad Complex Tachycardia