ACE Inhibitors and ARBs Flashcards

1
Q

Only ACEi 100% Renally excreted (no hepatic metabolism)

A

Lisinopril

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2
Q

Clinical Effects of ACEi and ARB

A
Vasodilation
Decrease catecholamine sensitivity 
Decrease Aldosterone Release
Decrease ADH Release
Decrease Na+/H+ Exchange in proximal tubules (Increasing Na+ excretion)
Decreased Sensation of Thirst
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3
Q

Unique Side Effects of ACE Inhibitors

A

Angioedema

Cough

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4
Q

Side Effects of ACE Inhibitors and ARBs

A

Hypotension
Hyperkalemia
Angioedema, Cough (ACEi only due to bradykinin synthesis)

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5
Q

Contraindications of ACE Inhibitors and ARBs

A

Pregnancy
Potassium Sparing diuretics
Severe CKD

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