Addiction Flashcards
What Is Addiction?
A disorder in which an individual takes a substance or engages in a behaviour that is pleasurable but eventually becomes compulsive with harmful consequences.
What is physical dependence?
Estate of the body due to habitual drug use and which results in a withdrawal syndrome when use of the drug is reduced or stopped.
Physical dependence occurs when withdrawal syndrome is produced.
What is psychological dependence?
A compulsion to continue taking a drug because it’s use is rewarding.
The person wants to experience the effects of the drug, increase pleasure or avoid discomfort. If psychological dependence occurs, the person will continuously take the drug until it becomes a habit, despite the harmful consequences.
What is tolerance?
Tolerance occurs when an individual’s response to a given amount of a drug is reduced. This means they need an even greater dose to produce the same effect on behaviour.
Tolerance is caused by repeated previous exposure to the effects of the drug.
What is cross-tolerance?
A type of tolerance where developing tolerance to one drug (alcohol, for example) can reduce sensitivity to another type (benzodiazepines - a sleep-inducing drug. These people need higher doses of this anaesthetic in surgery.
Cross tolerance can be used therapeutically by giving benzodiazepines to people withdrawing from alcohol to reduce the withdrawal syndrome.
What are risk factors for the development of an addiction?
A risk factor for addiction is an internal/external influence that increases an individual’s use of an addictive substance/behaviour.
They include:
- Genetic vulnerability,
- Genetic mechanisms,
- Stress,
- Personality,
- Family influences,
- Peers.
‘Describe and evaluate the risk factors for the development of an addiction’ (16) AO1?
A risk factor for addiction is an internal/external influence that increases an individual’s use of an addictive substance/behaviour.
Genetic vulnerability explains why, when someone is exposed to a drug, they become dependent whilst others do not. There are two genetic mechanisms that influence addiction; the lower the amount of D2 receptors on neurons, the higher the vulnerability to addictive substances because more substance is needed to release dopamine; and the lack of presence of an enzyme (CYP2A6) contributes to a lower risk of developing a nicotine addiction. If someone is genetically vulnerable, they have a predisposition to becoming an addict.
Epstein believed stress to be a risk factor. He found a strong correlation between individuals who suffered from post-traumatic stress disorder and alcohol addiction.
Personality traits are risk factors. Psychologists found there is a strong correlation between antisocial personality disorder (which involves impulsivity) and addiction-related behaviour.
Perceived parental approval (a family influence) is the extent to which an adolescent believes their parents have positive attitudes towards an addictive substance/behaviour. Adolescents who believe their parents have little interest in monitoring their behaviour were significantly more likely to develop an addiction.
O’Connell suggested three major risks in peer relationships for alcohol addiction; an adolescents norms and attitudes being influenced by peers; peers providing more opportunities to drink alcohol; and an adolescent over-estimating how much their peers are drinking and so drinks more to keep-up.
‘Describe and evaluate the risk factors for the development of an addiction’ (16) AO3?
Strength - Kendler et al Used data from the National Swedish adoption study. They looked at adults who had been adopted as children But who had a biological parent with an addiction. These people had a significantly greater risk of developing an addiction (8.6%) compared with adopted children adults with no addicted parent in their biological family (4.2%). This suggests a genetic vulnerability is an important risk factor.
Strength - Real life application. Hawkins et al believes that a focus on risk factors is a highly promising strategy for preventing and treating addictions. If we can understand what the risk factors are, then we have an opportunity to identify those in the population who are most at risk. Tobler et at created a peer-pressure resistance training program to help prevent young people taking up smoking. If we can identify individuals at risk, we can use programs like these to prevent addictions in future.
Weakness - Methodological issues. Assessing some of the major risk factors requires participants to recall incidence of stress, trauma, and family behaviours from the past. This may be difficult to recall accurately because of related stress, trauma or memory decay. This may reduce reliability of risk factors in the development of addiction.
Weakness - Research into risk factors is often correlation studies, which raises issues of cause and effect. Many studies have shown there was a strong correlation between stressful experiences and addiction related behaviours. However, many addictions can create greater levels of stress because of their generally negative effect on lifestyle, relationships, financial affairs and so on. It is difficult to separate the effects of an addiction and the causes of an addiction.
What Are The Explanations For Nicotine Addiction?
- Brain neurochemistry - the biological explanation.
2. Learning theory - psychological explanation.
What is withdrawal syndrome?
A collection of symptoms associated with abstaining from a drug or reducing its use.
They indicate that a physical dependence has developed.
For example, effects of nicotine withdrawal include anxiety, restlessness, increased appetite and weight gain.
These symptoms increase motivation for continuing to take the drug and therefore avoid the withdrawal symptoms. This is a secondary form of psychological dependence.
Explanation For Nicotine Addiction - Brain Neurochemistry AO1?
The brain neurochemistry explanation for nicotine addiction:
The ‘desensitisation hypothesis’ and ‘nicotine regulation model’ make up this explanation.
Desensitisation hypothesis: Acetylcholine receptors (ACh receptors) lie on neurons. There is a subtype of acetylcholine receptor called the nicotinic receptor (nAChR) receptors can be stimulated by ACh or nicotine.
When nAChRs are activated by nicotine, the neuron transmits dopamine along the mesolimbic pathway to the nucleus accumbens (NA), triggering the release of more dopamine to the frontal cortex.
The VTA is made up of the mesolimbic pathway and NA - the VTA generally has more nAChR receptors than other areas of the brain.
nAChRs are desensitised after, which leads to downregulation (a reduction in the number of active neurons). At this point, the nAChR is said to be desentisied. Whilst a person is smoking, nAChRs are continuously desensitised.
However, once nicotine leaves the bloodstream, nAChRs can become available again (resensitise), causing a person to experience withdrawal as nAChRs become overstimulated by ACh as nicotine no longer binds to them. This is upregularion.
Repetition of this process overtime creates chronic desensitisation of nAChR. This can only be overcome by increasing nicotine intake. Tolerance develops.
The process of withdrawal and tolerance is called ‘the nicotine regulation model’.
Explanation for nicotine addiction - brain neurochemistry AO3?
Strength - the neurochemistry explanation is the ability to apply the explanation in the real-world.
After nicotine was identified as the addictive component in cigarettes, nicotine replacement therapy (NRT) products (e.g. patches) were produced. NRTs work because nicotine enters the bloodstream via the product and binds to nAChRs, causing dopamine to release and cause euphoria. Withdrawal effects are reduced gradually by reducing nicotine intake over a period of weeks, allowing smokers to stop smoking. The understanding of the neurochemistry explanation has allowed addicts to be treated.
Weakness - the explanation is criticized for being biologically reductionist. The explanation suggests humans become addicted to nicotine due to the dopamine reward system; a biological process beyond our control. This suggests nicotine addiction is inevitable when a person starts smoking. Gilbert provided research support that concluded withdrawal symptoms depend much more on the environment and personality of a person. For example, people who are neurotic generally experience worse withdrawal symptoms than people who are emotionally stable. This research suggests other factors, such as personality and environment influences nicotine addiction.
Weakness - the theory only considers the role of dopamine. Research shows that there are many other neurochemical mechanisms involved such as neurotransmitters GABA and serotonin (5-HT), plus other systems such as endogenous opioids (endorphins). This suggests that the explanations is limited and more research should be conducted to understand the roles of other neurochemical systems and their association with nicotine addiction.
Explanation for nicotine addiction - the psychological learning theory AO1?
Nicotine addiction can be explained by reinforcement. Nicotine stimulates the release of dopamine, resulting in euphoria (positive reinforcement). The smoker will then avoid withdrawal effects (e.g. anxiety) and so nicotine use is maintained (negative reinforcement). Cue reactivity further enforces nicotine addiction. The pleasure experienced is a primary reinforcer due to the dopamine reward system. Any other stimuli present at the time of nicotine intake also becomes associated with the pleasurable effect and therefore, becomes a secondary reinforcer. The secondary reinforcer (e.g. cigarette packet) then produces the same effects as nicotine.
Explanation for nicotine addiction - the psychological learning theory AO3?
Strength - the learning approach is the ability to apply the explanation to the real-world.
Aversion therapy uses counterconditioning to treat nicotine addiction by associating the pleasant effects of smoking with an aversive stimulus (electric shock). Research by Smoith found this to be effective; 52% of participants were still abstaining after one year using this method, compared to the usual 20-25% of people who abstain without using this method. This research shows that knowledge of the learning approach has allowed for a successful treatment for nicotine addiction.
Strength - There is further research to support the learning explanation for nicotine addiction. Carter and Tiffany conducted a meta-analysis of 41 studies into cue reactivity. The analysis showed that dependent smokers acquired the most psychological arousal to the cues, even without nicotine being present. Both investigations show how the learning explanation has resulted in a successful treatment for nicotine addiction.
Weakness - gender bias (ISSUES AND DEBATES). Women are generally less successful at giving up smoking than men. Carpenter et al suggested that young women are more sensitive to smoking related cues, which makes it more difficult for them to stop smoking and prevent relapse. This could be explained by self efficacy. It may be that female smokers have less confidence in their ability to give up smoking, which undermines their attempts to do so.
What is behavioural tolerance?
One type of tolerance is behavioural tolerance. It happens when an individual learns through experience to adjust their behaviour to compensate for the effects of a drug.
For example, people addicted to alcohol learn to walk more slowly when they are drunk to avoid falling over.