Acyclovir

Question 1

Acyclovir

Answer 1

Pharmacologic Class: Nucleoside Analogue

Therapeutic Class: Antiretroviral

Question 2

Action

Answer 2

Inhibits herpes virus replications by inhibiting DNA polymerase, premature termination of DNA synthesis.

Question 3

Use

Answer 3

To treat initial episodes of herpes genitalis.

To treat recurrent episodes of herpes genitalis intermittently.

To treat Varicella-Zoster infection in immunocompromised patients.

Treat HSV-1 and HSV-2 infections.

Question 4

Complications

Answer 4

Seizures

Acute renal failure

Hepatitis

Thrombocytopenia

Stevens-Johnson Syndrome

Coma

Question 5

Contraindications/Precautions

Answer 5

Hypersensitive to acyclovir or valacyclovir or their components.

Question 6

Interactions

Answer 6

Cimetidine

Probenecid

Mycophennolate Mofetil

Question 7

Client Education

Answer 7

Does not cure herpes infections, helps manage S/S

Seek medical attention if symptoms worsen

Increase fluid intake during treatment

Notify provider if become pregnant

Manage herpes outbreak at the first sign of symptoms.

Question 8

Dose

Answer 8

200mg/Q4 for 10 days